{"id":"W6960900217","doi":"10.1371/journal.pone.0303450.s006","title":"Clinical trial protocol.","year":2024,"lang":"en","type":"article","venue":"Figshare","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Reactogenicity; Immunogenicity; Seroconversion; Adverse effect; Tolerability; Randomized controlled trial; Clinical trial; Placebo","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002970361,0.0001744225,0.0001851883,0.00005947509,0.0001068807,0.00004484457,0.0002998062,0.0003500375,0.6085333],"category_scores_gemma":[0.0004672482,0.0001565646,0.0001901629,0.000170995,0.00003060216,0.0001760399,0.00009667336,0.00112954,0.02575773],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003994736,"about_ca_system_score_gemma":0.0001513163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":4.124833e-7,"about_ca_topic_score_gemma":0.000001055631,"domain_scores_codex":[0.9983425,0.0003117948,0.0004591046,0.0003910282,0.0001562825,0.0003392493],"domain_scores_gemma":[0.9987724,0.0007577939,0.00005099863,0.0001872025,0.00005509938,0.0001764998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00467423,0.0002242423,0.00001932133,0.0003499337,0.0001127566,0.0002353185,0.00004511384,0.0001050989,0.00002639017,0.00008106006,0.8591194,0.1350072],"study_design_scores_gemma":[0.01289548,0.0002460783,0.00003596197,0.0002897474,0.00002929158,0.000008179326,0.000004929979,0.004286383,0.0004576045,0.0001201656,0.9814441,0.0001820752],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"protocol","genre_scores_codex":[0.001214989,0.001517973,0.0001177656,0.001320412,0.01339137,0.309487,0.468136,0.003175309,0.2016392],"genre_scores_gemma":[0.03160263,0.00003313784,0.0006160669,0.008113969,0.009840894,0.879208,0.05020883,0.0001970537,0.02017947],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.5827756,"threshold_uncertainty_score":0.9750009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4332935417993725,"score_gpt":0.5971224464960418,"score_spread":0.1638289046966693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}