{"id":"W6963882433","doi":"10.23645/epacomptox.20384181","title":"Urinary MicroRNA Biomarkers of Nephrotoxicity Demonstrate Different Variability and Directionality in Exosomal Fraction Compared to Whole (Unfractionated) Urine","year":2022,"lang":"en","type":"other","venue":"U.S. Environmental Protection Agency","topic":"Migration, Education, Indigenous Social Dynamics","field":"Social Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Nephrotoxicity; Directionality; Urinary system; Urine; microRNA; Presentation (obstetrics)","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008355928,0.0003065724,0.0003710886,0.000391289,0.0008554145,0.00003315254,0.0001852274,0.0003341667,0.01271085],"category_scores_gemma":[0.00006859247,0.0003778398,0.0001070521,0.0004076391,0.0003355643,0.0001917763,0.00008064272,0.0004292584,0.00003254158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002390492,"about_ca_system_score_gemma":0.0002161798,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.02945514,"about_ca_topic_score_gemma":0.02243448,"domain_scores_codex":[0.9967901,0.001109883,0.0005313169,0.0006544763,0.0005925537,0.0003216779],"domain_scores_gemma":[0.9989317,0.00006616877,0.0005414218,0.0002796802,0.00001490287,0.0001661004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007589331,0.01224631,0.8668796,0.0006568715,0.000720139,0.00001394395,0.04609973,0.0003156336,0.03676237,0.0007071791,0.01310812,0.02173119],"study_design_scores_gemma":[0.0004268539,0.0001394849,0.8513039,0.00004145725,0.00004677947,0.000007089201,0.003663737,0.00007269176,0.0001648547,0.001073411,0.1425465,0.0005132061],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.955977,0.0001613748,0.000880094,0.000466618,0.000818355,0.004670244,0.0004820177,0.0001718658,0.03637247],"genre_scores_gemma":[0.9741344,0.000322041,0.0003523701,0.0000333041,0.0002341317,0.0005960987,0.0003362723,0.0001179877,0.02387341],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1294384,"threshold_uncertainty_score":0.9998674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01267238856977005,"score_gpt":0.2546347895369172,"score_spread":0.2419624009671472,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}