{"id":"W6964100050","doi":"10.25345/c5rr1q02z","title":"MassIVE MSV000096916 - Characterization of conformational dynamics and allostery of the catalytic domain of human mitochondrial YME1L protease","year":2025,"lang":"en","type":"dataset","venue":"California Digital Library","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Allosteric regulation; Domain (mathematical analysis); Dynamics (music); Catalysis; Protease; Characterization (materials science); Protein dynamics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00002913871,0.0001979561,0.0003185941,0.00008929036,0.00003825753,0.00002744643,0.0002789882,0.0003428187,0.00006411342],"category_scores_gemma":[0.00007102964,0.0001570085,0.000147374,0.00008994183,0.000278896,0.00002512759,0.0003721416,0.0001235262,0.0000027907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006989904,"about_ca_system_score_gemma":0.0002607352,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000024385,"about_ca_topic_score_gemma":0.000001727762,"domain_scores_codex":[0.9988974,0.00005829268,0.0005575786,0.0002283568,0.000145258,0.0001131472],"domain_scores_gemma":[0.9988716,0.000021531,0.0005670359,0.0004259722,0.00006376627,0.0000500463],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006947198,0.000185824,0.0008664044,0.001503022,0.0001953996,0.000003450682,0.00001645072,0.000003088208,0.2257559,0.0004101085,0.7701495,0.0002160614],"study_design_scores_gemma":[0.001462858,0.0004670576,0.0003341643,0.0003840122,0.0001311198,0.00002621831,0.00003996732,0.00002131,0.1339708,0.0003553836,0.8623964,0.0004107011],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.03620215,0.00003648279,0.0001193686,0.0000749363,0.0003029223,0.0005010629,0.9624242,0.000003344345,0.0003355034],"genre_scores_gemma":[0.004600509,0.00002888413,0.00003656131,0.0001239213,0.0001585651,0.00002300476,0.9944204,0.00001043622,0.0005977099],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.09224687,"threshold_uncertainty_score":0.6402622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004264036819364886,"score_gpt":0.1973201976838611,"score_spread":0.1930561608644962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}