{"id":"W6964115282","doi":"10.25345/c5np1wv52","title":"MassIVE MSV000093052 - H2A.Z histone variants facilitate HDACi-dependent removal of H3.3K27M mutant protein in paediatric high-grade glioma cells","year":2023,"lang":"en","type":"dataset","venue":"UC San Diego","topic":"","field":"","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill Genome Centre","funders":"","keywords":"Mutant; Histone; Glioma; Mutation; Cell culture; Suppressor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000724871,0.002018321,0.002114692,0.001763235,0.0007257679,0.001907185,0.002319619,0.002125029,0.03492136],"category_scores_gemma":[0.003286518,0.0005410116,0.001830541,0.002649352,0.0002831252,0.0005129549,0.001333663,0.001051,0.02949851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001317348,"about_ca_system_score_gemma":0.001826239,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02324745,"about_ca_topic_score_gemma":0.04286426,"domain_scores_codex":[0.9993298,0.00007957934,0.00005980202,0.0002626393,0.0001430093,0.0001252378],"domain_scores_gemma":[0.999276,0.0002617914,0.00008744087,0.0001436019,0.0001421433,0.00008907887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008795809,0.00004653003,0.005965268,0.001895045,0.0004148872,0.0001179833,0.00003609414,0.001270811,0.001540061,0.0004681753,0.9800933,0.007272193],"study_design_scores_gemma":[0.003180944,0.0002194667,0.04265856,0.001078754,0.001306768,0.0006710731,0.0001730557,0.004184383,0.006078448,0.003947292,0.936385,0.000116273],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.001454841,0.0004670337,0.0001051541,0.000127849,0.00003456056,0.00001088716,0.9964532,0.000499811,0.0008467738],"genre_scores_gemma":[0.002887744,0.0002019208,0.0003648913,0.0001041976,0.000007817538,0.00006025928,0.9955232,0.00008876347,0.0007611369],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.03492136,"threshold_uncertainty_score":0.1168237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02192855739765663,"score_gpt":0.2612931381887519,"score_spread":0.2393645807910952,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}