{"id":"W6964491620","doi":"10.3205/15dgrh234","title":"Long-term (104-Week) Efficacy and Safety Profile of Apremilast, an Oral Phosphodiesterase 4 Inhibitor, in Patients With Psoriatic Arthritis: Results From a Phase III, Randomized, Controlled Trial and Open-Label Extension (PALACE 1)","year":2015,"lang":"en","type":"article","venue":"German Medical Science (German Research Foundation)","topic":"Forest Ecology and Biodiversity Studies","field":"Agricultural and Biological Sciences","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Western Hospital","funders":"","keywords":"Apremilast; Safety profile; Psoriatic arthritis; Placebo; Randomized controlled trial; Clinical trial; Adverse effect; Rheumatoid arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.009613774,0.000201652,0.0009382815,0.0001001431,0.000782266,0.000249907,0.0006191726,0.0001422097,0.0001832272],"category_scores_gemma":[0.004502023,0.00008442932,0.00003037559,0.0007207326,0.003774764,0.001018769,0.0007757082,0.0003641032,0.00001569199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008442441,"about_ca_system_score_gemma":0.0002770709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007464028,"about_ca_topic_score_gemma":0.002167359,"domain_scores_codex":[0.995261,0.0009471252,0.0007501679,0.0007478675,0.001734109,0.0005596952],"domain_scores_gemma":[0.9966345,0.001705586,0.0002688037,0.0001494489,0.0006202877,0.000621363],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9192842,0.002875982,0.006821332,0.000007293515,0.00003780311,0.00003323187,0.0009657221,2.610841e-7,0.000131239,0.0000988255,0.0002609546,0.06948314],"study_design_scores_gemma":[0.8410142,0.00386322,0.1538058,0.0001789037,0.00002405428,0.000002186795,0.0001747587,0.0004084197,0.00004088842,0.0002281277,0.00007624143,0.0001831691],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994234,0.000125214,0.000002865498,0.001193297,0.0001827433,0.004085235,0.00005616793,0.00001885839,0.0001016123],"genre_scores_gemma":[0.9990573,0.0001868706,0.0001063462,0.00009337309,0.0001072103,0.0001021516,0.0002852668,0.000001396121,0.00006006523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1469845,"threshold_uncertainty_score":0.9989364,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06517008747215224,"score_gpt":0.3572458386726607,"score_spread":0.2920757512005084,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}