{"id":"W6966901580","doi":"10.48448/93gc-vg64","title":"Enhancing the potassium chloride co-transporter KCC2 reverses functional deficits associated with Alzheimer's disease-related mutations in mice","year":2021,"lang":"en","type":"other","venue":"Underline Science Inc.","topic":"","field":"","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Cotransporter; Morris water navigation task; Hippocampal formation; GABAA receptor; Genetically modified mouse; Hippocampus; Fear conditioning; Prefrontal cortex; Intracellular; In vivo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001511225,0.0006559954,0.0005649597,0.001191189,0.0006239332,0.0002385894,0.0008520287,0.0002913731,0.003097107],"category_scores_gemma":[0.0005229946,0.0004932728,0.0001357373,0.004760304,0.002196352,0.0003736016,0.00008147968,0.0009365958,0.0005604457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006233265,"about_ca_system_score_gemma":0.003716657,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008514781,"about_ca_topic_score_gemma":0.01933922,"domain_scores_codex":[0.994584,0.0002247868,0.0007806341,0.001364421,0.002027864,0.00101828],"domain_scores_gemma":[0.9973036,0.0004006581,0.0007766093,0.0007117714,0.0004624176,0.0003449169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.002679923,0.01264307,0.1674014,0.0008282406,0.01302071,0.007898713,0.01772498,0.1537254,0.1376827,0.01888649,0.464514,0.002994356],"study_design_scores_gemma":[0.01837863,0.0007718371,0.7641453,0.02127341,0.01247236,0.0004805634,0.01851333,0.03365582,0.0181593,0.002604696,0.09550092,0.01404378],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.398066,0.02024896,0.006036406,0.008525045,0.01439972,0.01508197,0.01346579,0.007037695,0.5171384],"genre_scores_gemma":[0.9494114,0.00003900787,0.0006415132,0.0004820781,0.0003224144,0.0001496765,0.004858978,0.0009329275,0.04316203],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.5967439,"threshold_uncertainty_score":0.9997519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02777590322970632,"score_gpt":0.2722295484166395,"score_spread":0.2444536451869332,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}