{"id":"W6971120","doi":"10.1007/978-1-4939-1130-1_14","title":"Systems-Wide Analysis of Protein Ubiquitylation: We Finally Have the Tiger by the Tail","year":2014,"lang":"en","type":"book-chapter","venue":"","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Tiger; Ubiquitin; Computational biology; Chemistry; Biology; Cell biology; Computer science; Genetics; Gene; Algorithm","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007781902,0.0005596456,0.0009138328,0.0004097061,0.0003054074,0.001948514,0.0006273599,0.0008615682,0.004058171],"category_scores_gemma":[0.0003154315,0.0003132919,0.0005129676,0.0007478623,0.0009807681,0.002162529,0.0007803746,0.002642877,0.002012554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006720431,"about_ca_system_score_gemma":0.000322534,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004409004,"about_ca_topic_score_gemma":0.001491637,"domain_scores_codex":[0.9997786,0.00003234008,0.0000112977,0.00008711768,0.00006859571,0.00002204868],"domain_scores_gemma":[0.9998287,0.00007164053,0.0000114097,0.00003932854,0.00002451873,0.00002428935],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003224161,0.00007591432,0.001444838,0.001182465,0.0001804162,0.0001667216,0.0001636942,0.001111324,0.4944563,0.06065801,0.0682852,0.3719527],"study_design_scores_gemma":[0.00002184246,0.0001693793,0.006427021,0.0001934805,0.000128267,0.001162756,0.0001078253,0.003890184,0.2139265,0.09286674,0.6810169,0.00008908575],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04873817,0.6002346,0.2535363,0.02219201,0.005201909,0.00008866721,0.003458084,0.004364892,0.06218539],"genre_scores_gemma":[0.2361127,0.3331502,0.2092134,0.02340116,0.002939734,0.0001877247,0.004637646,0.001745143,0.1886124],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004058171,"threshold_uncertainty_score":0.01357597,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01680146927356843,"score_gpt":0.2266198764646939,"score_spread":0.2098184071911254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}