{"id":"W6977320569","doi":"10.6084/m9.figshare.17254230","title":"Additional file 1 of Predicting heterogeneity in clone-specific therapeutic vulnerabilities using single-cell transcriptomic signatures","year":2021,"lang":"en","type":"article","venue":"Figshare","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Transcriptome; Pairwise comparison; Drug response; False discovery rate; Cancer cell lines; Cell; Cell survival","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001768839,0.001653282,0.001243833,0.00182956,0.0008240612,0.002026195,0.002054552,0.001477807,0.7480091],"category_scores_gemma":[0.01829633,0.0006326609,0.001082691,0.002244791,0.00030287,0.001598125,0.001283741,0.001224992,0.1534274],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001046453,"about_ca_system_score_gemma":0.001719969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004605214,"about_ca_topic_score_gemma":0.01118452,"domain_scores_codex":[0.9993454,0.00008472545,0.00008345025,0.0002200356,0.0001797588,0.00008673871],"domain_scores_gemma":[0.9874045,0.009544916,0.0005366112,0.001007224,0.001204094,0.0003025785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005098383,0.0001320598,0.005242437,0.003350559,0.0001223685,0.0001951408,0.00008204822,0.002071138,0.001053903,0.0009942054,0.9715958,0.01465066],"study_design_scores_gemma":[0.005503191,0.0006252667,0.04404277,0.003042834,0.0003467139,0.001196842,0.0005761251,0.02089647,0.00725993,0.02187794,0.8942979,0.0003340241],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0002756206,0.0000206136,0.0007617857,0.00006324737,0.0000239921,0.00004048063,0.9972801,0.00112802,0.0004060999],"genre_scores_gemma":[0.008171141,0.0001026231,0.006018581,0.0003641118,0.00005843383,0.0008010823,0.979466,0.001552177,0.003465798],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.7480091,"threshold_uncertainty_score":0.3594344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0439393812174995,"score_gpt":0.2363013220831379,"score_spread":0.1923619408656385,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}