{"id":"W6977378163","doi":"10.6084/m9.figshare.c.7823207","title":"Genome-Wide Methylation Sequencing to Identify DNA Methylation Markers for Early-stage Hepatocellular Carcinoma in Liver and Blood","year":2025,"lang":"en","type":"other","venue":"Figshare","topic":"Japanese History and Culture","field":"Social Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Hepatocellular carcinoma; Cirrhosis; DNA methylation; Methylation; Carcinoma; Real-time polymerase chain reaction; Epigenetics; Cohort","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006468025,0.0002699621,0.0003744315,0.0007419381,0.0001653454,0.0003710533,0.0002238119,0.0003373086,0.001125868],"category_scores_gemma":[0.0009615357,0.0002052109,0.0003383826,0.0005056479,0.0001296683,0.0001309431,0.0003096186,0.0003616718,0.0003188499],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002372319,"about_ca_system_score_gemma":0.0002594134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001467341,"about_ca_topic_score_gemma":0.002844129,"domain_scores_codex":[0.9996676,0.00008490559,0.00002235969,0.0001177537,0.00007058604,0.00003678209],"domain_scores_gemma":[0.9996104,0.000131125,0.00008872811,0.00003795655,0.00008783249,0.00004404045],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001383084,0.0001016313,0.4025136,0.0004651117,0.0007356108,0.0003089971,0.0002092839,0.002257713,0.5195121,0.0004186159,0.002718091,0.06937619],"study_design_scores_gemma":[0.0001008887,0.0007982523,0.7967515,0.00009497039,0.0007735399,0.001417301,0.000226895,0.02630549,0.1601223,0.001485628,0.01187519,0.0000480615],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9727663,0.005062115,0.01467568,0.0002955931,0.00004618764,0.00006415014,0.005650368,0.0002577875,0.001181904],"genre_scores_gemma":[0.9855988,0.0006455905,0.008731941,0.0002380618,0.00003266074,0.00005958015,0.003752405,0.00002993216,0.0009109592],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001467341,"threshold_uncertainty_score":0.003766418,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04459532834248568,"score_gpt":0.2890295923663602,"score_spread":0.2444342640238745,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}