{"id":"W6977556023","doi":"10.6084/m9.figshare.26619925.v1","title":"Additional file 1 of [225Ac]Ac- and [111In]In-DOTA-trastuzumab theranostic pair: cellular dosimetry and cytotoxicity in vitro and tumour and normal tissue uptake in vivo in NRG mice with HER2-positive human breast cancer xenografts","year":2024,"lang":"en","type":"article","venue":"Figshare","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto","funders":"","keywords":"Cytotoxicity; In vivo; Human breast; In vitro; Cancer; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00149761,0.001134634,0.001122872,0.001494538,0.0006918121,0.001614257,0.001602125,0.001388546,0.8826224],"category_scores_gemma":[0.01347454,0.0007771763,0.0007161928,0.002397976,0.0002311928,0.00156218,0.0007851802,0.001058794,0.2607576],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0012601,"about_ca_system_score_gemma":0.001476067,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004286236,"about_ca_topic_score_gemma":0.00658229,"domain_scores_codex":[0.9995769,0.00006789298,0.00006066683,0.0001174941,0.0001195733,0.00005760541],"domain_scores_gemma":[0.9887993,0.008050757,0.0006397145,0.0006555123,0.001580885,0.0002738577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006212792,0.0001334668,0.001050841,0.003336125,0.00004208942,0.00008432898,0.00003495464,0.0006241568,0.0006329906,0.000975093,0.9799348,0.01252995],"study_design_scores_gemma":[0.003928904,0.0003405699,0.008292016,0.001724026,0.0001485137,0.0004952035,0.0001328752,0.001823425,0.003754855,0.00903286,0.9702096,0.0001171536],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"other","genre_scores_codex":[0.0001870605,0.0000522304,0.000664784,0.0001196128,0.00003474815,0.00008186825,0.9962593,0.000867708,0.001732635],"genre_scores_gemma":[0.008436913,0.0003608312,0.007301671,0.0008008105,0.0001132638,0.002065804,0.964045,0.002823089,0.01405257],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.8826224,"threshold_uncertainty_score":0.1674249,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01257868094547619,"score_gpt":0.2692109597773452,"score_spread":0.256632278831869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}