{"id":"W6978087172","doi":"10.6084/m9.figshare.23993130","title":"Additional file 1 of GTM-decon: guided-topic modeling of single-cell transcriptomes enables sub-cell-type and disease-subtype deconvolution of bulk transcriptomes","year":2023,"lang":"en","type":"article","venue":"Figshare","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Transcriptome; Hyperparameter; Deconvolution; Inference; Table (database); Transformation (genetics)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002057235,0.002660805,0.001363856,0.001275173,0.00105236,0.002125496,0.003052327,0.001639293,0.6741679],"category_scores_gemma":[0.01379138,0.0009351083,0.001684756,0.00217144,0.0004436359,0.001802603,0.001683015,0.001936805,0.2409676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001029431,"about_ca_system_score_gemma":0.001591621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004906188,"about_ca_topic_score_gemma":0.01067084,"domain_scores_codex":[0.9993079,0.0001124182,0.00005813033,0.0002897621,0.0001472799,0.0000845563],"domain_scores_gemma":[0.9938122,0.004354104,0.0001643745,0.000911425,0.0005944592,0.0001634639],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.000334033,0.00007890968,0.002149715,0.001567005,0.0001158014,0.00008346605,0.00008271761,0.003240784,0.002110033,0.00127585,0.9743043,0.01465733],"study_design_scores_gemma":[0.002770791,0.000351265,0.01815036,0.001064244,0.0002650882,0.0006739617,0.0003333816,0.05020569,0.02424787,0.02663841,0.8749824,0.0003165984],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0007024138,0.00005555578,0.008507427,0.000107896,0.00007879624,0.0000625783,0.9740726,0.01521592,0.001196814],"genre_scores_gemma":[0.008765681,0.000102458,0.0279645,0.0002982087,0.00007813775,0.0009274718,0.9386338,0.01853206,0.004697745],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.6741679,"threshold_uncertainty_score":0.4647599,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03823024563633213,"score_gpt":0.2256750752294428,"score_spread":0.1874448295931107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}