{"id":"W6981176075","doi":"","title":"Direct Observation of Hierarchical Folding in Single Riboswitch Aptamers","year":2008,"lang":"en","type":"article","venue":"NPARC","topic":"Medical History and Innovations","field":"Arts and Humanities","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Aptamer; Folding (DSP implementation); Riboswitch; Base sequence","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001581948,0.0001376696,0.0002339386,0.0002188025,0.0004124736,0.0003869732,0.000215716,0.0004050361,0.009742083],"category_scores_gemma":[0.0006073013,0.0002000253,0.0001506812,0.0002366655,0.0002213273,0.0002465239,0.0003036139,0.0007956454,0.001829366],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001971284,"about_ca_system_score_gemma":0.0001960742,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004474453,"about_ca_topic_score_gemma":0.000929602,"domain_scores_codex":[0.9997645,0.00001785882,0.000005332999,0.00008081481,0.00008899808,0.00004243741],"domain_scores_gemma":[0.9995887,0.0001466745,0.00004941884,0.00007470817,0.00008548465,0.00005508346],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001092655,0.0000240286,0.0006922311,0.00006011854,0.000006991776,0.000244242,0.00009585472,0.0001430592,0.9903795,0.000599648,0.001233419,0.006411791],"study_design_scores_gemma":[0.00001262545,0.0001008243,0.003962051,0.000004012661,0.000005870384,0.0002199854,0.00008266408,0.001651502,0.9896352,0.0002106816,0.004107099,0.000007366932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9457621,0.0004595798,0.01746171,0.0005948888,0.0002824547,0.00007118359,0.0005047559,0.0005264884,0.03433687],"genre_scores_gemma":[0.9760765,0.0001667838,0.005360413,0.0002624416,0.00002663588,0.00003649906,0.0004198416,0.0001252878,0.01752566],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009742083,"threshold_uncertainty_score":0.03259051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09423510287733798,"score_gpt":0.2362325048263478,"score_spread":0.1419974019490098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}