{"id":"W6981436247","doi":"","title":"Electrochemical Detection of Platinum-Based Chemoresistance and Correlation with MEK1 Activity in Living Cancer Cells","year":2024,"lang":"en","type":"other","venue":"Mspace (University of Manitoba)","topic":"Knowledge Management and Sharing","field":"Social Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Ovarian cancer; Biomarker; Cancer; Cancer cell; Mechanism (biology); Drug resistance; Kinase; Chemotherapy; Acquired resistance","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001412755,0.00008991411,0.0001760379,0.0002130349,0.00005529463,0.0000111728,0.00009887846,0.0001378882,0.00003115121],"category_scores_gemma":[0.00001044646,0.0001117643,0.00002902105,0.0002743379,0.0001452525,0.00006714852,0.00004166933,0.0001422853,0.000004474],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001571892,"about_ca_system_score_gemma":0.00005262233,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.01194521,"about_ca_topic_score_gemma":0.884714,"domain_scores_codex":[0.9994172,0.00004419063,0.00003785671,0.0001971184,0.000180721,0.0001229383],"domain_scores_gemma":[0.9996906,0.00004570089,0.0001400636,0.00007449999,0.00002397825,0.00002519162],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002145945,0.001070769,0.493036,0.01542491,0.0013894,0.0001563675,0.03750683,0.0003278801,0.3212526,0.003966848,0.08311833,0.0406041],"study_design_scores_gemma":[0.007510933,0.0009063464,0.417716,0.03230015,0.002833538,0.000001214774,0.1344059,0.04116115,0.08047441,0.0006758474,0.276798,0.005216517],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.3756494,0.001273876,0.01025006,0.0003352201,0.0003055746,0.0007277369,0.00001479711,0.0001843016,0.6112591],"genre_scores_gemma":[0.9535037,0.0001477247,0.0002497839,0.00000162076,0.00004624015,4.939983e-7,9.223189e-7,0.00003564356,0.04601381],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.8727688,"threshold_uncertainty_score":0.9946343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00942236127823235,"score_gpt":0.2092885390728555,"score_spread":0.1998661777946231,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}