{"id":"W6983336536","doi":"","title":"MANNICH BASES OF CYCLOALKANONES AND RELATED COMPOUNDS AS CYTOTOXIC AGENTS","year":2023,"lang":"en","type":"dissertation","venue":"University Library (University of Saskatchewan)","topic":"Ferrocene Chemistry and Applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Cancer Institute; University of Alberta","keywords":"Mannich base; Cytotoxicity; Cyclohexanone; Mannich reaction; Selectivity; Cyclopentanone; Cytotoxic T cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001174165,0.0003231332,0.0001528032,0.0002965101,0.0001485684,0.000188665,0.0001860731,0.0001986816,0.00225925],"category_scores_gemma":[0.000123756,0.0001047995,0.0001405841,0.0002351024,0.0001347232,0.0002302824,0.0001791769,0.0003659547,0.0005258855],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002907357,"about_ca_system_score_gemma":0.0002090905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003711619,"about_ca_topic_score_gemma":0.001285211,"domain_scores_codex":[0.9999135,0.00001898475,0.000008365211,0.00001461873,0.00002607897,0.00001846213],"domain_scores_gemma":[0.9999381,0.000007340998,0.0000160633,0.000006672247,0.00001604226,0.00001564835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002948329,0.0001350744,0.0003229727,0.0005905351,0.0000142882,0.0001910026,0.00007862335,0.001572397,0.9582577,0.00478528,0.0004923684,0.0332649],"study_design_scores_gemma":[0.00003661857,0.002680079,0.00120415,0.00008295616,0.00002346565,0.0003412291,0.0000512536,0.0009010875,0.9515064,0.0004925595,0.04265814,0.00002192916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9223456,0.02764275,0.01178569,0.0002578206,0.0002162108,0.0003837109,0.0005865908,0.0001941187,0.03658755],"genre_scores_gemma":[0.9649048,0.01155166,0.01079282,0.0001378171,0.00004955392,0.0001688545,0.0003754955,0.00001859417,0.01200044],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00225925,"threshold_uncertainty_score":0.007557988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00796449550376903,"score_gpt":0.1903354810230712,"score_spread":0.1823709855193022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}