{"id":"W6983353661","doi":"","title":"Mechanism of action of novel single arm alkylating \"combi-molecules\" and bi-functional \"bis-combi-molecules\"","year":2008,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Supramolecular Chemistry and Complexes","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"McGill University Health Centre; McGill University","keywords":"Action (physics); Mechanism of action; Mechanism (biology)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005455707,0.00015311,0.00009935783,0.00005695618,0.0000970843,0.0001455056,0.0002105801,0.0002526382,0.003959898],"category_scores_gemma":[0.0000652228,0.00006796778,0.0001328467,0.00004917133,0.00008293556,0.0002166428,0.00009308786,0.0002297374,0.0006561649],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001338737,"about_ca_system_score_gemma":0.00008600115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002433416,"about_ca_topic_score_gemma":0.0005176574,"domain_scores_codex":[0.9999734,0.000003599565,0.000001382691,0.00000716998,0.00000593189,0.00000837161],"domain_scores_gemma":[0.999981,0.000003710471,0.00000534881,0.000001777935,0.000002940624,0.000005119181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00041386,0.0001117146,0.0001160301,0.0004175977,0.00001077223,0.0001218048,0.00003157288,0.0004953036,0.9765189,0.002273968,0.001778712,0.01770963],"study_design_scores_gemma":[0.00003652941,0.0007726462,0.0007521525,0.00001352477,0.00001207675,0.0001502262,0.00001580421,0.002310348,0.9824324,0.0001317741,0.01336369,0.000008805452],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9581732,0.00666985,0.006333626,0.0006146802,0.0003331068,0.0001417488,0.0006842058,0.0002175241,0.02683199],"genre_scores_gemma":[0.9800249,0.002367456,0.002724797,0.0001765744,0.00001806769,0.00008881693,0.0002529414,0.00001124815,0.01433527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003959898,"threshold_uncertainty_score":0.01324719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0331085127044766,"score_gpt":0.2403567023568297,"score_spread":0.2072481896523531,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}