{"id":"W6987024543","doi":"","title":"The role of endoplasmic reticulum BIK in p53-mediated apoptosis /","year":2005,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Unfolded protein response; Endoplasmic reticulum; Apoptosis; Programmed cell death; Apoptosome; Cytochrome c; Proteases; Mitochondrion","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001470737,0.0002995121,0.0001695273,0.0004899052,0.0005401889,0.0007125271,0.0002374591,0.0003669593,0.01449301],"category_scores_gemma":[0.0001027777,0.000150384,0.0002147665,0.000220804,0.0001903119,0.0003382189,0.00038693,0.0004730122,0.005538573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007854343,"about_ca_system_score_gemma":0.0005878934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002516454,"about_ca_topic_score_gemma":0.00351111,"domain_scores_codex":[0.9999067,0.00001207691,0.000006253547,0.00001501841,0.00002588251,0.00003419435],"domain_scores_gemma":[0.9999453,0.000006798497,0.00001024119,0.000004283271,0.00001260908,0.00002079146],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002991504,0.0005212253,0.00206063,0.001136525,0.00006072123,0.001379463,0.0002310399,0.0005426069,0.8160571,0.009701769,0.01283477,0.1524827],"study_design_scores_gemma":[0.0005620474,0.001819853,0.08942725,0.0005447916,0.0001424744,0.002645141,0.0007040704,0.002979015,0.6107048,0.005104115,0.2853056,0.00006086708],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6530046,0.1041704,0.004635851,0.009852968,0.001395698,0.0002377625,0.003119406,0.0004321626,0.2231512],"genre_scores_gemma":[0.6329519,0.03976213,0.002636777,0.0006274352,0.0001306127,0.00009492991,0.002480358,0.00007502022,0.3212409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01449301,"threshold_uncertainty_score":0.04848397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00439910194582956,"score_gpt":0.2062741556617033,"score_spread":0.2018750537158737,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}