{"id":"W69871636","doi":"10.1016/s0092-8674(01)00244-6","title":"Amyotrophic Lateral Sclerosis","year":2001,"lang":"en","type":"review","venue":"Cell","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":431,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal General Hospital","funders":"","keywords":"Amyotrophic lateral sclerosis; SOD1; Biology; Spinal cord; Neuroscience; Progressive muscular atrophy; Brainstem; Atrophy; Motor neuron; Spinal muscular atrophy; Disease; Missense mutation; Degenerative disease; Pathology; Central nervous system disease; Medicine; Mutation; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002116216,0.0006227277,0.002344415,0.0003419365,0.0001051491,0.00008016363,0.0004314598,0.0006840146,0.003306329],"category_scores_gemma":[0.00003020184,0.0004393063,0.0009846037,0.0008133012,0.0001459037,0.00007244351,0.000253591,0.001242776,0.006067981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004384941,"about_ca_system_score_gemma":0.0004067523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005416428,"about_ca_topic_score_gemma":0.000001292466,"domain_scores_codex":[0.9967973,0.0001817361,0.0007301636,0.0007569278,0.0006655855,0.0008683471],"domain_scores_gemma":[0.9980724,0.00008396211,0.0002151837,0.001000904,0.000109976,0.0005176109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002358929,0.0002257995,0.00002111873,0.02202867,0.0001608646,0.0003990323,0.00002035291,2.090424e-7,0.00006841919,0.000007892321,0.01260899,0.964435],"study_design_scores_gemma":[0.0005630535,0.0001913708,0.0001825187,0.01415773,0.0007573341,0.0001460083,0.000001095381,0.000004757918,0.000005280034,0.00001212306,0.9835849,0.0003937543],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001883064,0.9828432,0.000005249019,0.0001286275,0.0002655493,0.001223375,0.00002449005,0.0001509904,0.0151702],"genre_scores_gemma":[0.00008791309,0.9633707,0.0001990639,0.0001438413,0.0008988984,0.000145841,0.0002341887,0.0001891652,0.03473032],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.970976,"threshold_uncertainty_score":0.9998059,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1286976837106233,"score_gpt":0.3527965896593125,"score_spread":0.2240989059486893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}