{"id":"W6989710288","doi":"","title":"Can BioSAXS detect ultrastructural changes of antifungal compounds in Candida albicans?","year":2023,"lang":"en","type":"article","venue":"Dokumentenrepositorium der RUB (Ruhr University Bochum)","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Infection and Immunity; Ruhr-Universität Bochum; Bundesministerium für Bildung und Forschung","keywords":"Antifungal; Yeast; Ultrastructure; Flucytosine; Antimicrobial; Drug resistance; Fluconazole; Mode of action; Antifungal drugs","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002012208,0.0002442489,0.0003518542,0.0004341005,0.0002553341,0.00006087315,0.0004035586,0.0001423766,0.0001372197],"category_scores_gemma":[0.00002040549,0.0002464929,0.00009140097,0.0008832299,0.0001939785,0.000225764,0.0001486201,0.0001865166,0.0000221907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002627371,"about_ca_system_score_gemma":0.00009452977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005957241,"about_ca_topic_score_gemma":0.004121094,"domain_scores_codex":[0.9982143,0.0001117743,0.0002497257,0.0004780531,0.000430264,0.000515876],"domain_scores_gemma":[0.9991556,0.00006413429,0.0001835808,0.0003389435,0.0001166877,0.0001410556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001649507,0.00002128106,0.03242441,0.00005794462,0.00003543784,0.0001731855,0.00100379,0.00006864157,0.9636073,0.0002323118,0.002039608,0.0001711586],"study_design_scores_gemma":[0.001690714,0.0002955383,0.1993254,0.00007937686,0.0001043451,0.00008210339,0.002807116,0.0001334839,0.7909946,0.0001561366,0.003815342,0.0005157669],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948642,0.00003985484,0.000038651,0.000398657,0.002469924,0.0002160469,0.0001015246,0.0001690381,0.001702158],"genre_scores_gemma":[0.9981198,0.00002409791,0.0001829486,0.00004996655,0.0002400771,0.000001485208,0.00006143556,0.00001775687,0.0013024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1726126,"threshold_uncertainty_score":0.9999987,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008518822959559259,"score_gpt":0.2002890660189261,"score_spread":0.1917702430593669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}