{"id":"W6989710288","doi":"","title":"Can BioSAXS detect ultrastructural changes of antifungal compounds in Candida albicans?","year":2023,"lang":"en","type":"article","venue":"Dokumentenrepositorium der RUB (Ruhr University Bochum)","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Infection and Immunity; Ruhr-Universität Bochum; Bundesministerium für Bildung und Forschung","keywords":"Antifungal; Yeast; Ultrastructure; Flucytosine; Antimicrobial; Drug resistance; Fluconazole; Mode of action; Antifungal drugs","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003805624,0.0004574825,0.000270045,0.0007118152,0.0002425828,0.0005530988,0.0003417199,0.0007079536,0.00160181],"category_scores_gemma":[0.0003928345,0.0002795609,0.0003802133,0.0006497548,0.0003755904,0.0005591689,0.0004096157,0.0007463159,0.0005535081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002406041,"about_ca_system_score_gemma":0.000172541,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007937492,"about_ca_topic_score_gemma":0.001001141,"domain_scores_codex":[0.9997463,0.00003419757,0.00001535206,0.00005679034,0.0001073903,0.00004002664],"domain_scores_gemma":[0.9996839,0.0000717708,0.00008411695,0.00002730748,0.00009623192,0.00003669349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001507898,0.00002640262,0.002339649,0.0001985263,0.0000254881,0.00008669637,0.00006573935,0.000119656,0.9914049,0.0001076155,0.0002447944,0.005229672],"study_design_scores_gemma":[0.0000113691,0.0002739419,0.0596263,0.0000459476,0.00006749243,0.0006466677,0.000302487,0.003677775,0.9307768,0.0002862573,0.004244225,0.00004086972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9644077,0.007281334,0.02090981,0.0006467135,0.0001278073,0.00006808855,0.001920293,0.0007009215,0.003937303],"genre_scores_gemma":[0.9458293,0.007501146,0.04015239,0.000532319,0.00005474111,0.0001107159,0.002666162,0.0001452692,0.003007835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00160181,"threshold_uncertainty_score":0.005358577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008518822959559259,"score_gpt":0.2002890660189261,"score_spread":0.1917702430593669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}