{"id":"W6990619212","doi":"","title":"Effectiveness of dabrafenib in the treatment of patients with <i>BRAF </i>V600-mutated metastatic melanoma in a Named Patient Program","year":2019,"lang":"en","type":"article","venue":"UWA Profiles and Research Repository (UWA)","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Metastatic melanoma; Dabrafenib; Melanoma; Radiation therapy; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003245599,0.0001675118,0.0004922028,0.0001888507,0.0002018604,0.0004707872,0.0001656886,0.0002501529,0.002196585],"category_scores_gemma":[0.0006526352,0.00006942345,0.000578907,0.0001827133,0.0001190706,0.000277271,0.0001263252,0.0005498024,0.0002531878],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006138866,"about_ca_system_score_gemma":0.0004767176,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00154172,"about_ca_topic_score_gemma":0.006006007,"domain_scores_codex":[0.9998338,0.00007399302,0.00001051518,0.0000215721,0.0000212719,0.00003887881],"domain_scores_gemma":[0.9997197,0.00005323494,0.00005077931,0.00001346008,0.00001823622,0.0001446098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.1751875,0.00570281,0.1369846,0.0004037058,0.00155657,0.00088474,0.0001517872,0.004524414,0.009900387,0.001138593,0.01776952,0.6457955],"study_design_scores_gemma":[0.05251281,0.1397672,0.7454906,0.0003663104,0.002516154,0.00368608,0.0005470944,0.006668642,0.007093414,0.001376967,0.03986132,0.0001134279],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871345,0.005664415,0.00007941126,0.001192607,0.00008090927,0.00005317126,0.000977937,0.00002593286,0.004791022],"genre_scores_gemma":[0.9959769,0.001545741,0.000136745,0.0003478111,0.00004781611,0.00002166109,0.0009494472,0.00000430368,0.0009696565],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002196585,"threshold_uncertainty_score":0.007348299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01135371363391633,"score_gpt":0.2704309587925473,"score_spread":0.259077245158631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}