{"id":"W6990738739","doi":"","title":"Efficacy of alirocumab according to background statin type and dose: pooled analysis of 8 ODYSSEY Phase 3 clinical trials.","year":2017,"lang":"en","type":"article","venue":"Prodinra (INRA Bordeaux-Aquitaine)","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"Alirocumab; Pooled analysis; Statin; Evolocumab; PCSK9; Meta-analysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.01114943,0.0004020809,0.003361083,0.0005891277,0.0002900902,0.0001101692,0.0004458385,0.0002636123,0.0001279032],"category_scores_gemma":[0.01270352,0.0003253922,0.0009950829,0.001041554,0.0002864957,0.0002257121,0.0003530599,0.0003969361,0.00001335496],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008030348,"about_ca_system_score_gemma":0.0005443254,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001177945,"about_ca_topic_score_gemma":0.00009559934,"domain_scores_codex":[0.9946157,0.0006809493,0.002308475,0.000879126,0.0009277129,0.0005879775],"domain_scores_gemma":[0.9940662,0.0006915487,0.001340501,0.002324031,0.0009746753,0.0006030732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0166991,0.003369071,0.07624633,0.001689956,0.02149548,0.0001411912,0.001385913,0.00007720762,0.0142988,0.002376887,0.0008125085,0.8614076],"study_design_scores_gemma":[0.07721483,0.01190694,0.8251244,0.001283365,0.05070613,0.00006424928,0.003381241,0.004454934,0.007088778,0.0003694171,0.01677468,0.001631083],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921705,0.001700013,0.001221473,0.001193244,0.0003321857,0.002294098,0.0000873679,0.0000524051,0.0009487108],"genre_scores_gemma":[0.9947558,0.0006348887,0.003343358,0.000250885,0.0005730098,0.00004895329,0.0001054183,0.00005927059,0.0002284404],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8597765,"threshold_uncertainty_score":0.9999198,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1677035256669517,"score_gpt":0.4978317254126866,"score_spread":0.3301281997457348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}