{"id":"W6990738739","doi":"","title":"Efficacy of alirocumab according to background statin type and dose: pooled analysis of 8 ODYSSEY Phase 3 clinical trials.","year":2017,"lang":"en","type":"article","venue":"Prodinra (INRA Bordeaux-Aquitaine)","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"Alirocumab; Pooled analysis; Statin; Evolocumab; PCSK9; Meta-analysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01052367,0.00169417,0.006603568,0.00114719,0.0003366903,0.00171152,0.0007774323,0.001150568,0.002339533],"category_scores_gemma":[0.01071066,0.0008368862,0.01382877,0.001456345,0.0005780678,0.001256132,0.0009793866,0.00164905,0.0003098793],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007095365,"about_ca_system_score_gemma":0.0008178155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001392281,"about_ca_topic_score_gemma":0.005102526,"domain_scores_codex":[0.9943376,0.00349651,0.0008423314,0.0006481421,0.000431897,0.000243544],"domain_scores_gemma":[0.992357,0.003938267,0.002318016,0.0006545468,0.0003920201,0.0003401486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.6037456,0.000244631,0.01893997,0.009760853,0.3323965,0.00007352036,0.00009179227,0.001382074,0.002145307,0.0001301348,0.002115616,0.02897415],"study_design_scores_gemma":[0.2424129,0.0152536,0.1140111,0.001310282,0.6180214,0.0002564191,0.0001478098,0.001749438,0.001300879,0.0009865329,0.004388981,0.0001606079],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5902712,0.3910425,0.003034259,0.001132405,0.0006828064,0.001191794,0.009099108,0.0002316759,0.00331413],"genre_scores_gemma":[0.9664013,0.02534015,0.001790344,0.0009245724,0.0002958324,0.0007248963,0.003624212,0.00007205709,0.0008266445],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01052367,"threshold_uncertainty_score":0.05565518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1677035256669517,"score_gpt":0.4978317254126866,"score_spread":0.3301281997457348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}