{"id":"W6991099180","doi":"","title":"EVALUATION OF PHENYLALANINE ISOTOPES USING AN ISOLATED ORGAN PERFUSION MODEL","year":2023,"lang":"en","type":"dissertation","venue":"University Library (University of Saskatchewan)","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Phenylalanine; Tyrosine; Hydroxylation; Isotopomers; Perfusion; Phenylalanine hydroxylase; Metabolism; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006139498,0.001140525,0.0009650324,0.0004462139,0.0002862195,0.0005503346,0.0006392712,0.0008047118,0.001706823],"category_scores_gemma":[0.0004079976,0.0002552236,0.0005442465,0.0003596242,0.0004530142,0.0005800889,0.0003452863,0.001167331,0.0004489622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005270344,"about_ca_system_score_gemma":0.0005604984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001223227,"about_ca_topic_score_gemma":0.001234298,"domain_scores_codex":[0.999626,0.00006981083,0.00001371027,0.000122207,0.00009959737,0.00006861521],"domain_scores_gemma":[0.999474,0.0001262173,0.0001303475,0.0000615752,0.0001014485,0.0001065507],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004845708,0.00008325377,0.0001661954,0.00006028178,0.00001526727,0.00009351738,0.0000171663,0.0001995323,0.9970619,0.00006197867,0.00003263005,0.001723725],"study_design_scores_gemma":[0.00005026958,0.00311968,0.001801202,0.000009420204,0.0001384338,0.0003267626,0.00003201921,0.003576085,0.989556,0.00005051487,0.001317939,0.00002155161],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9483319,0.004260305,0.04431374,0.0001711326,0.000175156,0.0002153574,0.0004596452,0.0003218101,0.001750966],"genre_scores_gemma":[0.9490362,0.004475731,0.03994052,0.0001461668,0.000109311,0.0004005025,0.0010742,0.0001218814,0.00469548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001706823,"threshold_uncertainty_score":0.005709827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01590001664438532,"score_gpt":0.2180184094924164,"score_spread":0.2021183928480311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}