{"id":"W6991377930","doi":"","title":"GERMLINE & SOMATIC VARIATION IN GASTROINTESTINAL MALIGNANCIES","year":2017,"lang":"en","type":"dissertation","venue":"TSpace (University of Toronto)","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Germline; Pancreatic cancer; Somatic cell; Gastrointestinal cancer; Exome; Population; Colorectal cancer; Exome sequencing; Germline mutation; Genome","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001558719,0.0001006311,0.0001195523,0.0004987108,0.0002212602,0.0003362239,0.0001391712,0.0002331225,0.003103703],"category_scores_gemma":[0.0004325132,0.00007172806,0.0001125358,0.0006123039,0.0002557488,0.00007497882,0.0001900533,0.0001998251,0.0004150276],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002597247,"about_ca_system_score_gemma":0.0001708648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002436914,"about_ca_topic_score_gemma":0.006516119,"domain_scores_codex":[0.9998166,0.00001718168,0.00001529028,0.00007027285,0.00005394006,0.00002677165],"domain_scores_gemma":[0.9997831,0.0000529235,0.0000859261,0.00001945976,0.00002365055,0.00003501591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008315899,0.00006402871,0.553306,0.0002987053,0.0001954245,0.004316353,0.0003997837,0.001295342,0.3507517,0.002340732,0.004308157,0.08189216],"study_design_scores_gemma":[0.00002791666,0.0001098877,0.9612031,0.00004770758,0.00006629735,0.004715825,0.0001391658,0.001279947,0.02017589,0.0007676438,0.01145044,0.00001615594],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897249,0.000895119,0.001497878,0.0001928203,0.00002565226,0.00001432574,0.003709791,0.00005486428,0.003884747],"genre_scores_gemma":[0.9959345,0.0003237801,0.001086417,0.00009202729,0.00001868626,0.000006653358,0.001666559,0.00002270494,0.0008486466],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003103703,"threshold_uncertainty_score":0.01038295,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02083201547757662,"score_gpt":0.2798332495699931,"score_spread":0.2590012340924165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}