{"id":"W6991912802","doi":"","title":"Instrumental Analysis of Pasylated Asparaginase, JZP-341, A Pre-Clinical Drug Candidate","year":2023,"lang":"en","type":"other","venue":"York University Digital Library (York University)","topic":"","field":"","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs; York University","keywords":"Capillary electrophoresis; Pharmacokinetics; Biopharmaceutical; Pharmacodynamics; Drug; Enzyme; Drug discovery","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003812914,0.0004072481,0.0001736481,0.000742952,0.0002892866,0.0003380697,0.0002637299,0.0003983311,0.002444624],"category_scores_gemma":[0.000499312,0.0001205474,0.0002039144,0.0004211592,0.0003399348,0.0003338397,0.0001897464,0.0006504314,0.0007921408],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003502282,"about_ca_system_score_gemma":0.0002965418,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001012014,"about_ca_topic_score_gemma":0.001438232,"domain_scores_codex":[0.9997317,0.00003221986,0.00001032174,0.00005870021,0.0001411109,0.00002592235],"domain_scores_gemma":[0.9997768,0.00006380751,0.00005444889,0.00001701442,0.00006745211,0.00002051892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009048031,0.00003024209,0.0009618228,0.00006036906,0.00001397451,0.00006324102,0.00003316379,0.0001676293,0.9920541,0.0002580555,0.0002909972,0.005975973],"study_design_scores_gemma":[0.000004803266,0.00008905034,0.003062292,0.000005436739,0.00001343939,0.0001731724,0.00004151578,0.002245889,0.9912047,0.00008917135,0.003061373,0.000009161738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9043331,0.005374702,0.07496499,0.0005468974,0.00009972462,0.0001691896,0.002479561,0.0009222031,0.01110967],"genre_scores_gemma":[0.9445187,0.003103346,0.03834657,0.0003081825,0.00002090038,0.0001121907,0.00147506,0.0001840707,0.011931],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002444624,"threshold_uncertainty_score":0.008178055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01256372178517848,"score_gpt":0.2037232024928705,"score_spread":0.191159480707692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}