{"id":"W6992791314","doi":"","title":"Mechanisms of oncogene induced senescence in MAPK- driven cancer development","year":2020,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"McGill University","keywords":"Senescence; Malignancy; Cancer; Lung cancer; Mutation; Adenocarcinoma; Cell growth; Cancer cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004919263,0.0005593533,0.0002345112,0.0005963612,0.0003293806,0.0006187679,0.0004499538,0.0004896232,0.001186927],"category_scores_gemma":[0.0002387274,0.0003189271,0.0004412416,0.0001646357,0.0005058846,0.0006170239,0.0007458573,0.000822266,0.0006435313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006914842,"about_ca_system_score_gemma":0.0003152147,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003296055,"about_ca_topic_score_gemma":0.0003397214,"domain_scores_codex":[0.9996289,0.0000819057,0.00003288071,0.00007668207,0.0001089163,0.00007065495],"domain_scores_gemma":[0.9997278,0.00002702524,0.0001021258,0.00004417368,0.00004197108,0.00005694266],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001008915,0.00003675601,0.000644283,0.0001380079,0.000006022273,0.0001825837,0.00005488069,0.0001668727,0.9925677,0.002235764,0.00007728811,0.003789007],"study_design_scores_gemma":[0.0000332487,0.0008711376,0.01730077,0.00007212104,0.0000282471,0.001943479,0.0001210716,0.003349539,0.9549842,0.002303722,0.01895457,0.00003799124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.937014,0.02219218,0.02994783,0.0005143911,0.0001425773,0.000199042,0.0006905201,0.0005196333,0.008779869],"genre_scores_gemma":[0.9842899,0.005829163,0.004288875,0.00009543467,0.00002974057,0.0001271154,0.0003087984,0.00003254001,0.004998395],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001186927,"threshold_uncertainty_score":0.005017102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03103423998248838,"score_gpt":0.2776095700082878,"score_spread":0.2465753300257994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}