{"id":"W69944306","doi":"10.1161/circ.120.suppl_18.s1153-a","title":"Abstract 5808: Endothelial Cell Polyploidization Induces an Atherogenic Phenotype and is Prevented by Activating the Nampt-SIRT1 Axis","year":2009,"lang":"en","type":"article","venue":"Circulation","topic":"Lipid metabolism and disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"Medicine; Phenotype; Cell; Cancer research; Internal medicine; Cell biology; Endocrinology; Genetics; Gene; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001315199,0.0003554112,0.00044697,0.0002271304,0.0001513318,0.0002395381,0.0002628498,0.0003167327,0.006719542],"category_scores_gemma":[0.00009619327,0.0001529206,0.0003043483,0.0001953203,0.0002284727,0.0001822128,0.0002528033,0.0007465929,0.001334274],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002396905,"about_ca_system_score_gemma":0.0002030433,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004312683,"about_ca_topic_score_gemma":0.0004665974,"domain_scores_codex":[0.9998751,0.00001588112,0.00001587252,0.00003732983,0.00003077995,0.0000250954],"domain_scores_gemma":[0.9999005,0.000009715959,0.00003482868,0.000009420964,0.000009254725,0.00003626534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003457257,0.0000338848,0.000080291,0.00007303575,0.000007555243,0.00004704269,0.000009315806,0.00001982025,0.9971597,0.00007628066,0.0002311912,0.001916172],"study_design_scores_gemma":[0.0001511437,0.0009319203,0.007068565,0.00002037871,0.00003358185,0.0003704128,0.00002682049,0.0007242256,0.980492,0.0001218328,0.01005211,0.000007078862],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9781412,0.003596373,0.005942295,0.0007068487,0.0002298867,0.00008414478,0.00439891,0.0007458808,0.006154318],"genre_scores_gemma":[0.9742786,0.001664488,0.003823848,0.0003447831,0.0000536751,0.0001704188,0.004947065,0.0001466526,0.01457049],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.006719542,"threshold_uncertainty_score":0.02247906,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01484692840171356,"score_gpt":0.2574288085846304,"score_spread":0.2425818801829168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}