{"id":"W6997365837","doi":"","title":"Why Maintain Light Chain Isotypes? The Influence of Heavy Chain Isotype and Complementary Determining Region Lengths upon Light Chain Isotype in Xenopus laevis","year":2016,"lang":"en","type":"dissertation","venue":"OakTrust (Texas A&M University Libraries)","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Smiths Detection (Canada)","funders":"College of Veterinary Medicine and Biomedical Sciences, Texas A and M University; National Institutes of Health; National Science Foundation","keywords":"Isotype; Immunoglobulin class switching; Heavy chain; Context (archaeology); Immunogenetics; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004380137,0.0007784526,0.001123526,0.0008174501,0.000691718,0.00005905894,0.001248875,0.001279337,0.0006515622],"category_scores_gemma":[0.0001047164,0.0006574278,0.0002163991,0.000624454,0.0005790291,0.000638656,0.0005508689,0.001203709,0.0001503565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001883325,"about_ca_system_score_gemma":0.0003392543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001094144,"about_ca_topic_score_gemma":0.002179321,"domain_scores_codex":[0.996143,0.0009720857,0.0007741902,0.001017341,0.0001382906,0.0009550257],"domain_scores_gemma":[0.9974792,0.0005359048,0.0008569598,0.0009008629,0.0001444298,0.00008267081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01617916,0.001038906,0.02137089,0.001273435,0.002128193,0.0007785779,0.01750205,0.00003679521,0.8174831,0.08184449,0.02466015,0.01570433],"study_design_scores_gemma":[0.007537023,0.001753071,0.01090462,0.001942421,0.0005317326,0.0001419643,0.01638905,0.00002373243,0.1893363,0.002109325,0.7672704,0.002060293],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9819298,0.005614929,0.0000322895,0.004362841,0.001093197,0.000992836,0.0001535363,0.0001367428,0.005683846],"genre_scores_gemma":[0.97535,0.00246289,0.00006956818,0.0007898496,0.00008968537,0.000006749019,0.001068753,0.000090104,0.02007241],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7426103,"threshold_uncertainty_score":0.9995877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007836384147593592,"score_gpt":0.1951197226987254,"score_spread":0.1872833385511318,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}