{"id":"W6999185796","doi":"","title":"Characterization of ABC transporters in both mammalian cells (ABCG2, ABCC2)and «plasmodium falciparum (Pgh1)»","year":2008,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Abcg2; ATP-binding cassette transporter; Multidrug resistance-associated protein 2; Transporter; Drug; Drug resistance; Transfection; Function (biology); Drug development","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001605233,0.0001683738,0.0001718671,0.0002341488,0.0001503417,0.0002531544,0.0001499585,0.0002287279,0.001690243],"category_scores_gemma":[0.0001818342,0.0001177508,0.0002057251,0.0003193116,0.0000971936,0.0002138286,0.0001003958,0.0003634246,0.0009327671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001643314,"about_ca_system_score_gemma":0.0001514995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000727472,"about_ca_topic_score_gemma":0.000754872,"domain_scores_codex":[0.9999081,0.0000133972,0.000009172499,0.00002009811,0.00003574092,0.00001352219],"domain_scores_gemma":[0.9999303,0.0000198109,0.00001152555,0.000007755656,0.00002350876,0.000007132067],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000008896664,0.000004356899,0.0001700601,0.00003646278,0.000001166349,0.00003789141,0.00001725177,0.00003543524,0.9976986,0.00009163431,0.00008902592,0.001809221],"study_design_scores_gemma":[0.000004602491,0.0001427565,0.007131032,0.00001180367,0.000009322299,0.0006889061,0.0000658215,0.0006124555,0.9692656,0.0001021349,0.02195714,0.000008421393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9567016,0.005570096,0.02656003,0.000627804,0.00008477004,0.0001741664,0.002824833,0.0002303906,0.00722637],"genre_scores_gemma":[0.9253592,0.006069906,0.03430254,0.0002987802,0.00003841427,0.0002760789,0.009826086,0.000143099,0.02368586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001690243,"threshold_uncertainty_score":0.005654395,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0113080921977849,"score_gpt":0.2206111073973082,"score_spread":0.2093030151995234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}