{"id":"W7000641288","doi":"","title":"Functional validation of morphological and gene expression changes related to metabolic adaptation in chemoresistant triple negative breast cancer cells","year":2019,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Cancer Research Society; McGill University; TD Bank","keywords":"Triple-negative breast cancer; Mitochondrion; Lipid metabolism; Gene expression; Cancer cell; Breast cancer; Cancer; Mitochondrial biogenesis; Regulation of gene expression; Gene expression profiling","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001536135,0.000221886,0.0002500623,0.0002160104,0.0001872631,0.0002486344,0.0001074029,0.0002276827,0.0009007625],"category_scores_gemma":[0.0001445682,0.00009360592,0.0002149129,0.0002742449,0.0001780946,0.0001449194,0.0001321454,0.0002615679,0.0002902923],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002082386,"about_ca_system_score_gemma":0.0001247568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007013047,"about_ca_topic_score_gemma":0.0006634703,"domain_scores_codex":[0.9998672,0.00001915968,0.00001550534,0.00003490097,0.0000419596,0.00002127894],"domain_scores_gemma":[0.9998437,0.00003485139,0.00004031051,0.00002743443,0.00003051721,0.00002320868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002474209,0.000008530471,0.0001728937,0.00001177951,0.000001253093,0.00001821338,0.00001422334,0.00001843007,0.9994886,0.0000155852,0.000004579542,0.0002210153],"study_design_scores_gemma":[0.000006766294,0.0003065665,0.02151621,0.00000385495,0.00001617534,0.0002779168,0.0001091508,0.0006524051,0.9756376,0.00002773908,0.001440151,0.000005568605],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994871,0.0004597074,0.002595955,0.00005943898,0.00001502232,0.00003018323,0.001080173,0.0000520918,0.0008363571],"genre_scores_gemma":[0.9902691,0.0005628518,0.003822756,0.00005004435,0.000005892435,0.0001078066,0.002266355,0.00003059774,0.00288471],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009007625,"threshold_uncertainty_score":0.003013372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01429811425921083,"score_gpt":0.2405771114036427,"score_spread":0.2262789971444318,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}