{"id":"W7000766738","doi":"","title":"Functional Analysis of the Contribution of HIF-1Îą Proline 402 to the Interaction with VHL","year":2016,"lang":"en","type":"dissertation","venue":"TSpace (University of Toronto)","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Cycloheximide; Hydroxylation; Transcription factor; Ubiquitin; In vitro; Proline; Functional analysis; Transcription (linguistics)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009147916,0.0002625663,0.0001121011,0.0001094896,0.0001866585,0.0001741334,0.0001733057,0.0001948347,0.001125313],"category_scores_gemma":[0.00007521592,0.00007840536,0.0001687734,0.0001470026,0.0001552246,0.0001115631,0.00009941972,0.0002413729,0.0003655755],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005132146,"about_ca_system_score_gemma":0.0001309872,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00244268,"about_ca_topic_score_gemma":0.001671525,"domain_scores_codex":[0.9999363,0.00001004684,0.000004203738,0.00001382014,0.00001645354,0.00001916191],"domain_scores_gemma":[0.9999391,0.0000111959,0.0000149264,0.00000512389,0.000006355704,0.00002338904],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002010409,0.00001741523,0.0002871213,0.00001776017,0.000003651342,0.0000677816,0.000007374113,0.0000531045,0.9988721,0.00006148978,0.00002849588,0.0003825946],"study_design_scores_gemma":[0.0000179596,0.0001643027,0.01556541,0.000003572439,0.00001335064,0.0005780515,0.00002820869,0.002011186,0.9787068,0.00004527926,0.002861249,0.000004651543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980925,0.0004215355,0.0005309695,0.00005955631,0.000009346974,0.000004141386,0.0004025009,0.000009540858,0.000469982],"genre_scores_gemma":[0.9958642,0.0002846592,0.0006300173,0.0000351608,0.000005913805,0.000006656035,0.001119219,0.00001178536,0.002042454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00244268,"threshold_uncertainty_score":0.004856884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005815035630144159,"score_gpt":0.2299001328123431,"score_spread":0.224085097182199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}