{"id":"W7000886779","doi":"","title":"Generación de un modelo de Células de Purkinje de cerebelo para el estudio de dos enfermedades raras: PLAN y ARSACS","year":2022,"lang":"en","type":"dissertation","venue":"Repository of Digital Objects for Teaching Research and Culture (University of Valencia)","topic":"Neurological diseases and metabolism","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Neurodegeneration; C9orf72; Induced pluripotent stem cell; Purkinje cell; Autophagy; Cerebellar ataxia; Cerebellum; Progeria","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0006658062,0.0002945627,0.0004734784,0.0002488057,0.001414064,0.000149076,0.0007882501,0.0003267247,0.000009295396],"category_scores_gemma":[0.001053283,0.0003126268,0.000342626,0.0002233912,0.0003455364,0.0004256735,0.0001954028,0.001182541,6.142216e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002985084,"about_ca_system_score_gemma":0.0008692459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002340239,"about_ca_topic_score_gemma":0.00003739775,"domain_scores_codex":[0.9968712,0.000555923,0.0002276693,0.0006818254,0.0007759847,0.0008873357],"domain_scores_gemma":[0.9983284,0.0004489832,0.0002749992,0.0002945232,0.0001573018,0.0004957744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003038514,0.001644466,0.007479114,0.001860196,0.0002338873,0.001097862,0.04343468,0.0006796637,0.923955,0.003802526,0.001268816,0.0115053],"study_design_scores_gemma":[0.00938139,0.01206329,0.1932413,0.001830957,0.00202661,0.001943644,0.157021,0.01406904,0.4898576,0.09827727,0.01605161,0.004236266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937119,0.001035152,0.0004219881,0.0000581428,0.00008659115,0.0005222672,0.0002536329,0.00006471707,0.003845534],"genre_scores_gemma":[0.9926926,0.0006363345,0.0005951534,0.00004797334,0.0001240964,0.0000108815,0.00009996417,0.0000344441,0.005758551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4340974,"threshold_uncertainty_score":0.9999326,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05282195941574924,"score_gpt":0.3261109298692064,"score_spread":0.2732889704534571,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}