{"id":"W7001929350","doi":"","title":"MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration","year":2025,"lang":"en","type":"article","venue":"Cronfa (Swansea University)","topic":"Fetal and Pediatric Neurological Disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"HORIZON EUROPE European Innovation Council; National Institute of General Medical Sciences; National Key Research and Development Program of China; European Regional Development Fund; Staatssekretariat für Bildung, Forschung und Innovation; Fundação para a Ciência e a Tecnologia; Japan Society for the Promotion of Science; HORIZON EUROPE Framework Programme; Directorate for Biological Sciences; National Institutes of Health; Junta de Andalucía; Novo Nordisk Fonden; National Estuarine Research Reserve System; Universität des Saarlandes; Office of Science; Shanghai Jiao Tong University; Natural Sciences and Engineering Research Council of Canada; Ministry of Education, India; Medical Research Council; National Natural Science Foundation of China; National Research Foundation of Korea; Deutsche Forschungsgemeinschaft; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Consejo Nacional de Ciencia y Tecnología; Swansea University; Fonds Wetenschappelijk Onderzoek; National Health and Medical Research Council; European Commission; Fundação de Amparo à Pesquisa do Estado de São Paulo; Australian Government; Leibniz-Gemeinschaft; Agence Nationale de la Recherche; U.S. Department of Energy; National Science Foundation; UK Research and Innovation; Division of Chemical, Bioengineering, Environmental, and Transport Systems; Department of Biotechnology, Ministry of Science and Technology, India; Austrian Science Fund; Vlaamse regering; National Research Foundation; U.S. Department of Agriculture; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; H2020 Marie Skłodowska-Curie Actions; University of Illinois at Urbana-Champaign; Ministry of Education and Science of Ukraine; Werner Siemens-Stiftung; Ministry of Science and ICT, South Korea; Novo Nordisk; Deutsches Zentrum für Infektionsforschung; Biotechnology and Biological Sciences Research Council; Danmarks Grundforskningsfond; Alexander von Humboldt-Stiftung; Agencia Nacional de Investigación y Desarrollo; Innovationsfonden; Ministerio de Ciencia, Innovación y Universidades; Fonds National de la Recherche Luxembourg; University Grants Commission","keywords":"Gene cluster; Cluster (spacecraft); Gene; Data curation; Genome; Identification (biology)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01968984,0.004957179,0.00451976,0.01013839,0.002749525,0.009538127,0.006060267,0.002533612,0.02186806],"category_scores_gemma":[0.03102889,0.00233634,0.004501015,0.007820767,0.001460905,0.005401792,0.01388552,0.005094559,0.02795878],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001491091,"about_ca_system_score_gemma":0.009080557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006702488,"about_ca_topic_score_gemma":0.01016294,"domain_scores_codex":[0.9924734,0.002293839,0.0007050852,0.00218059,0.001668925,0.0006781482],"domain_scores_gemma":[0.9878791,0.003962225,0.0009266622,0.002986687,0.002388623,0.001856628],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.005054656,0.0006229015,0.01693479,0.01517851,0.004680453,0.0008345033,0.006101273,0.01123573,0.07603036,0.03504024,0.5851221,0.2431645],"study_design_scores_gemma":[0.001158357,0.0005346611,0.01038875,0.003200339,0.001593867,0.0006218387,0.001582332,0.03459277,0.03706751,0.05036651,0.8584031,0.00048996],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"software","genre_gemma":"methods","genre_scores_codex":[0.01851428,0.009938917,0.3138035,0.004448844,0.001733996,0.001239943,0.1736194,0.4482251,0.02847604],"genre_scores_gemma":[0.03174872,0.004335752,0.5510738,0.001611789,0.0003809501,0.0017245,0.350728,0.05369325,0.00470317],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.02186806,"threshold_uncertainty_score":0.1041311,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006798776369825526,"score_gpt":0.2459625092469994,"score_spread":0.2391637328771738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). 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