{"id":"W7001929350","doi":"","title":"MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration","year":2025,"lang":"en","type":"article","venue":"Cronfa (Swansea University)","topic":"Fetal and Pediatric Neurological Disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"HORIZON EUROPE European Innovation Council; National Institute of General Medical Sciences; National Key Research and Development Program of China; European Regional Development Fund; Staatssekretariat für Bildung, Forschung und Innovation; Fundação para a Ciência e a Tecnologia; Japan Society for the Promotion of Science; HORIZON EUROPE Framework Programme; Directorate for Biological Sciences; National Institutes of Health; Junta de Andalucía; Novo Nordisk Fonden; National Estuarine Research Reserve System; Universität des Saarlandes; Office of Science; Shanghai Jiao Tong University; Natural Sciences and Engineering Research Council of Canada; Ministry of Education, India; Medical Research Council; National Natural Science Foundation of China; National Research Foundation of Korea; Deutsche Forschungsgemeinschaft; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Consejo Nacional de Ciencia y Tecnología; Swansea University; Fonds Wetenschappelijk Onderzoek; National Health and Medical Research Council; European Commission; Fundação de Amparo à Pesquisa do Estado de São Paulo; Australian Government; Leibniz-Gemeinschaft; Agence Nationale de la Recherche; U.S. Department of Energy; National Science Foundation; UK Research and Innovation; Division of Chemical, Bioengineering, Environmental, and Transport Systems; Department of Biotechnology, Ministry of Science and Technology, India; Austrian Science Fund; Vlaamse regering; National Research Foundation; U.S. Department of Agriculture; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; H2020 Marie Skłodowska-Curie Actions; University of Illinois at Urbana-Champaign; Ministry of Education and Science of Ukraine; Werner Siemens-Stiftung; Ministry of Science and ICT, South Korea; Novo Nordisk; Deutsches Zentrum für Infektionsforschung; Biotechnology and Biological Sciences Research Council; Danmarks Grundforskningsfond; Alexander von Humboldt-Stiftung; Agencia Nacional de Investigación y Desarrollo; Innovationsfonden; Ministerio de Ciencia, Innovación y Universidades; Fonds National de la Recherche Luxembourg; University Grants Commission","keywords":"Gene cluster; Cluster (spacecraft); Gene; Data curation; Genome; Identification (biology)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004846445,0.0001287917,0.0001752194,0.0001017608,0.0001691435,0.00002236441,0.00009569118,0.0001184245,0.00009564511],"category_scores_gemma":[0.0000752999,0.0001236977,0.000080682,0.001119994,0.0001000595,0.000276963,0.00005765061,0.0001082853,0.00004066056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001672252,"about_ca_system_score_gemma":0.0002201555,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004530665,"about_ca_topic_score_gemma":0.00008069379,"domain_scores_codex":[0.9991625,0.00006349691,0.0001295312,0.0002922121,0.0001355559,0.0002167294],"domain_scores_gemma":[0.9995247,0.00004605224,0.00004871723,0.00018135,0.0001257865,0.00007344213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.02396603,0.004776211,0.2112165,0.002519037,0.00130835,0.003036221,0.003186718,0.005208138,0.1069702,0.3258989,0.2247485,0.08716519],"study_design_scores_gemma":[0.007584951,0.0009760555,0.02638847,0.0001022334,0.000884953,0.00003907682,0.001949476,0.001561206,0.006286514,0.005955345,0.947676,0.0005956966],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7865599,0.0004866379,0.03004211,0.01490226,0.0006071819,0.0006785137,0.00005974045,0.0002242733,0.1664394],"genre_scores_gemma":[0.9882393,0.0002536562,0.0009701735,0.002199379,0.00006621921,8.329031e-7,0.00005280654,0.000006419954,0.008211181],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7229275,"threshold_uncertainty_score":0.5044246,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006798776369825526,"score_gpt":0.2459625092469994,"score_spread":0.2391637328771738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). 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