{"id":"W7006472089","doi":"","title":"Ubiquitin Specific Protease 34 (USP34), a New Positive Regulator of Canonical Wnt/Î²-catenin Signalling","year":2010,"lang":"en","type":"dissertation","venue":"Library and Archives Canada (Government of Canada)","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Deubiquitinating enzyme; Wnt signaling pathway; Regulator; Ubiquitin; Transcription factor; Signalling; Hedgehog signaling pathway; Signal transduction; Ubiquitin ligase","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001548022,0.0003272634,0.0001643618,0.0004271093,0.0002844512,0.0005228668,0.0001590621,0.0001963962,0.001263437],"category_scores_gemma":[0.00008471202,0.0001283384,0.0001838719,0.0002579904,0.0002864838,0.0001497623,0.0001838187,0.0002838022,0.000384857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008947405,"about_ca_system_score_gemma":0.0005393694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002466383,"about_ca_topic_score_gemma":0.003751177,"domain_scores_codex":[0.9999171,0.000005497724,0.00000383885,0.00001774964,0.00003998232,0.00001582857],"domain_scores_gemma":[0.9999654,0.000003096275,0.000007430299,0.000002792379,0.000009853689,0.00001136359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001618358,0.00002138015,0.0006819221,0.0001151689,0.000008163184,0.0005103685,0.00003083252,0.0001820385,0.9654872,0.001609813,0.001725109,0.02946615],"study_design_scores_gemma":[0.00003975871,0.0001844972,0.0246931,0.0000303455,0.00005374574,0.002756444,0.00007145261,0.001158635,0.8338814,0.000639767,0.1364653,0.0000254726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8129396,0.1263567,0.01510161,0.00174121,0.0004405504,0.0001897578,0.002300644,0.001011716,0.03991832],"genre_scores_gemma":[0.9135557,0.03488288,0.007772901,0.0002676486,0.00009695004,0.00004295151,0.001942949,0.00005514341,0.04138283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002466383,"threshold_uncertainty_score":0.00649184,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004127350350696527,"score_gpt":0.1656760999601946,"score_spread":0.1615487496094981,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}