{"id":"W7007878809","doi":"","title":"APOE and BCHE as modulators of cerebral amyloid deposition: A florbetapir PET genome-wide association study","year":2014,"lang":"en","type":"article","venue":"eScholarship (California Digital Library)","topic":"Environmental Engineering and Cultural Studies","field":"Computer Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging; University of California, San Diego; National Institutes of Health; Genentech; IXICO; University of California, Los Angeles; Ipsen; U.S. Food and Drug Administration; Servier; Eisai; Bayer HealthCare; Northern California Institute for Research and Education; Pfizer; Biogen; BioClinica; Medpace; Elan; Novartis; Bristol-Myers Squibb; Eli Lilly and Company; AstraZeneca; Alzheimer's Association; Amorfix Life Sciences; Synarc; TauRx Pharmaceuticals; National Science Foundation","keywords":"Pathogenesis; Apolipoprotein E; Disease; Amyloid (mycology); Amyloid β; Cerebral cortex; Association (psychology); Alzheimer's disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001264273,0.00104828,0.0006498524,0.0007213153,0.0006951244,0.00108159,0.0006875556,0.001278082,0.00222157],"category_scores_gemma":[0.001259225,0.0005671008,0.001019371,0.001232112,0.0005653692,0.000421045,0.0005457493,0.0008864644,0.0003908371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002643681,"about_ca_system_score_gemma":0.0002507308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006318108,"about_ca_topic_score_gemma":0.005172831,"domain_scores_codex":[0.9995375,0.0001434853,0.00004915109,0.0001462673,0.00006556576,0.00005812284],"domain_scores_gemma":[0.9992387,0.0002961583,0.0001507699,0.0001187829,0.00007607564,0.0001193807],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01474804,0.000722206,0.9391856,0.0001232936,0.004591913,0.004494263,0.0008266622,0.0003571127,0.02353704,0.0003950063,0.0006128675,0.01040595],"study_design_scores_gemma":[0.0002360587,0.0003686477,0.9935845,0.00001593011,0.00195228,0.001459587,0.0001823522,0.0007036069,0.0006624261,0.0001881703,0.0006269919,0.00001945365],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981824,0.0009148477,0.0002278126,0.0001124744,0.00001358634,0.000009760878,0.0001499284,0.000008432984,0.000380946],"genre_scores_gemma":[0.9987543,0.0003112328,0.0002688624,0.00006305205,0.00003479502,0.000008049999,0.0001411017,0.000009444608,0.0004092564],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006318108,"threshold_uncertainty_score":0.01256269,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005432178136991215,"score_gpt":0.1733361800877008,"score_spread":0.1679040019507096,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}