{"id":"W7007878809","doi":"","title":"APOE and BCHE as modulators of cerebral amyloid deposition: A florbetapir PET genome-wide association study","year":2014,"lang":"en","type":"article","venue":"eScholarship (California Digital Library)","topic":"Environmental Engineering and Cultural Studies","field":"Computer Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging; University of California, San Diego; National Institutes of Health; Genentech; IXICO; University of California, Los Angeles; Ipsen; U.S. Food and Drug Administration; Servier; Eisai; Bayer HealthCare; Northern California Institute for Research and Education; Pfizer; Biogen; BioClinica; Medpace; Elan; Novartis; Bristol-Myers Squibb; Eli Lilly and Company; AstraZeneca; Alzheimer's Association; Amorfix Life Sciences; Synarc; TauRx Pharmaceuticals; National Science Foundation","keywords":"Pathogenesis; Apolipoprotein E; Disease; Amyloid (mycology); Amyloid β; Cerebral cortex; Association (psychology); Alzheimer's disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001604119,0.0002226379,0.0002564383,0.00006076647,0.0001438394,0.0005724181,0.0003960773,0.00005475114,0.00002020384],"category_scores_gemma":[0.0001529566,0.0001919859,0.00008512937,0.0002481465,0.0000358511,0.002375009,0.0004320311,0.0001996561,0.0001990971],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005385936,"about_ca_system_score_gemma":0.000009255616,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000406758,"about_ca_topic_score_gemma":7.760243e-7,"domain_scores_codex":[0.9985837,0.00006922701,0.000304703,0.0003809742,0.000385456,0.0002758912],"domain_scores_gemma":[0.999284,0.0001367854,0.0001316616,0.0002772104,0.00001609187,0.0001542661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00001539339,0.000275941,0.9944835,0.00003942106,0.0001289725,0.00001069035,0.000240598,0.0002114764,0.0002500909,0.0009997633,0.0001869718,0.003157143],"study_design_scores_gemma":[0.001288509,0.0006845089,0.9757501,0.00005427652,0.00004207148,0.00001740346,0.000177624,0.002277155,0.003238544,0.004602063,0.01114915,0.0007186102],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934863,0.0001518821,0.002543749,0.0004765018,0.00007491402,0.0002009756,0.00006735013,0.0002209339,0.002777418],"genre_scores_gemma":[0.9976293,0.00001098843,0.001543398,0.0002505395,0.00005548398,0.00001634228,0.00004279259,0.00002128878,0.000429894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01873346,"threshold_uncertainty_score":0.7828956,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005432178136991215,"score_gpt":0.1733361800877008,"score_spread":0.1679040019507096,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}