{"id":"W7008780917","doi":"","title":"Construction of a knockout mouse model for combined methylmalonic aciduria and homocystinuria, «cblC» type («Mmachc»)","year":2010,"lang":"en","type":"other","venue":"Library and Archives Canada (Government of Canada)","topic":"","field":"","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Mutant; Heterozygote advantage; Phenotype; Knockout mouse; Embryonic stem cell; Wild type; Gene targeting; Chimera (genetics); Gene knockout","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006466355,0.0007992942,0.0005452784,0.002597363,0.001114153,0.0006257825,0.001234921,0.001287304,0.01045886],"category_scores_gemma":[0.0001818894,0.0008293505,0.0007409242,0.0005923234,0.0007238687,0.0004485193,0.0007151207,0.001491779,0.004175511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001398572,"about_ca_system_score_gemma":0.001336137,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009281122,"about_ca_topic_score_gemma":0.02284082,"domain_scores_codex":[0.9994462,0.00004830001,0.00006515464,0.0001083738,0.000203051,0.0001289388],"domain_scores_gemma":[0.9996204,0.00003572934,0.00006545374,0.00005691603,0.00005178321,0.0001696577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004856927,0.0004078838,0.0007943444,0.0000913287,0.00003061568,0.0007990284,0.000156541,0.0001429558,0.9853484,0.002335042,0.00276449,0.006643697],"study_design_scores_gemma":[0.0006794026,0.001070448,0.0102446,0.0001257362,0.0001960328,0.004926232,0.0002162038,0.002709521,0.8602037,0.0005271334,0.1190269,0.00007407261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8814703,0.002664282,0.04815929,0.002159127,0.0007187797,0.00207992,0.02591813,0.002823573,0.0340067],"genre_scores_gemma":[0.6515539,0.003624327,0.08834001,0.0009466734,0.0001098667,0.003594483,0.02212784,0.001477264,0.2282257],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01045886,"threshold_uncertainty_score":0.03498834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004500497380206756,"score_gpt":0.1608441275028923,"score_spread":0.1563436301226855,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}