{"id":"W7010094886","doi":"","title":"Genetic and functional characterization of modulators of the inflammasome in infection and immunity","year":2013,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ontario HIV Treatment Network; Canadian Institutes of Health Research; McGill University Health Centre; Ontario Genomics; Genome Canada; Fonds Québécois de la Recherche sur la Nature et les Technologies; McGill University; Ontario Genomics Institute; University of Ottawa","keywords":"Inflammasome; Innate immune system; Inflammation; Immune system; Programmed cell death; Immunity; Effector; AIM2","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002838135,0.0004030387,0.0002605317,0.0003269927,0.000159453,0.000357467,0.0003439539,0.0003574724,0.001745675],"category_scores_gemma":[0.00023212,0.000201275,0.0003084574,0.0001889253,0.0002501548,0.0002565873,0.000245664,0.0007970211,0.0006287723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003697919,"about_ca_system_score_gemma":0.0002525118,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002697969,"about_ca_topic_score_gemma":0.0002571305,"domain_scores_codex":[0.9997671,0.00004595304,0.00003597736,0.00004081321,0.00006447665,0.00004570174],"domain_scores_gemma":[0.9997364,0.00005511146,0.00008307587,0.00003683068,0.00002462655,0.00006390749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007094173,0.00002131888,0.0001106444,0.00002077104,0.000002965098,0.00003989932,0.000005189597,0.00007664575,0.9988536,0.0001709695,0.00002256009,0.0006045547],"study_design_scores_gemma":[0.00004713963,0.0005069338,0.005712725,0.00001992187,0.00003766932,0.000900519,0.00003183324,0.001240195,0.9829186,0.0001621201,0.008412158,0.00001028126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9823486,0.005354371,0.007480443,0.0003257566,0.00007863712,0.0001508522,0.001357829,0.00008317197,0.002820266],"genre_scores_gemma":[0.985621,0.002769514,0.00556171,0.00008381033,0.0000279006,0.0001393166,0.001857064,0.00006112801,0.00387851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001745675,"threshold_uncertainty_score":0.005839825,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005737657906719286,"score_gpt":0.1929679255158198,"score_spread":0.1872302676091005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}