{"id":"W7017221814","doi":"","title":"The &alpha;TSR Domain of Plasmodium Circumsporozoite Protein Bound Heparan Sulfates and Elicited High Titers of Sporozoite Binding Antibody After Displayed by Nanoparticles","year":2023,"lang":"en","type":"article","venue":"DOAJ (DOAJ: Directory of Open Access Journals)","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Circumsporozoite protein; Heparan sulfate; Plasmodium falciparum; Malaria; Antibody; Fusion protein; Glycan; Titer; Infectious disease (medical specialty)","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009635301,0.0003974221,0.0001161194,0.00007703216,0.0000926381,0.0001597708,0.0001187574,0.0002455129,0.0008733477],"category_scores_gemma":[0.00005842042,0.0001050989,0.0001884741,0.00007509036,0.00009248497,0.0001004619,0.0001589017,0.0003771871,0.0003476049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002904434,"about_ca_system_score_gemma":0.0001219304,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000698971,"about_ca_topic_score_gemma":0.001120265,"domain_scores_codex":[0.9999335,0.000008836857,0.000004026761,0.00001303653,0.00001623673,0.00002436504],"domain_scores_gemma":[0.9999782,0.000003153878,0.000005138918,0.000002089345,0.000004279489,0.000007127717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004171101,0.00001514631,0.00008588436,0.00001795836,0.000003585979,0.00002434063,0.000008080051,0.00007392858,0.9987172,0.00006621146,0.00008590795,0.0008601128],"study_design_scores_gemma":[0.00001897557,0.0003163303,0.001780747,0.000004918178,0.0000136142,0.0001229404,0.00001659811,0.002362899,0.9926779,0.00003437578,0.002646816,0.000003877002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932923,0.0006587284,0.003435749,0.0001410461,0.00004013523,0.00002389054,0.0001198837,0.00004343691,0.002244793],"genre_scores_gemma":[0.9934133,0.0004242926,0.002080815,0.0001208485,0.00001093262,0.00001670604,0.0003462217,0.00001585387,0.003571166],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008733477,"threshold_uncertainty_score":0.002921641,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06361482905705529,"score_gpt":0.4760594199063717,"score_spread":0.4124445908493164,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}