{"id":"W7017687701","doi":"","title":"667C > T and 1298A > C polymorphisms of MTHFR do not predict response to methotrexate in patients with gestational trophoblastic neoplasia","year":2011,"lang":"en","type":"article","venue":"","topic":"Gestational Trophoblastic Disease Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Population and Public Health","funders":"","keywords":"Methylenetetrahydrofolate reductase; Methotrexate; Gestational trophoblastic neoplasia; Antimetabolite; Antifolate; Gestation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003214442,0.0003274233,0.000532101,0.0005286141,0.00006312018,0.00001382962,0.0001065252,0.00007331137,0.0009068999],"category_scores_gemma":[0.001363644,0.0002517733,0.00006161515,0.0004815807,0.000269116,0.0001199388,0.00009647942,0.0001473197,0.00008372647],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008667496,"about_ca_system_score_gemma":0.0002402603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007260805,"about_ca_topic_score_gemma":0.00008168825,"domain_scores_codex":[0.9974869,0.0001770732,0.0005719876,0.0005211224,0.0008552261,0.000387723],"domain_scores_gemma":[0.9978372,0.0007944636,0.0001675593,0.0003414488,0.0004733633,0.0003859586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1065199,0.002271095,0.8664356,0.0002759063,0.0005184109,0.00009271076,0.007655565,0.0002313401,0.01064988,0.001659369,0.001760823,0.001929402],"study_design_scores_gemma":[0.005674899,0.001593373,0.9910601,0.0003008338,0.0001938486,0.00001350081,0.0001366976,0.00002313332,0.0002909811,0.0001509239,0.0003189851,0.0002427193],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946012,0.00005372798,0.002048748,0.0004078515,0.00008503289,0.0007574856,0.0002189921,0.00004829911,0.001778589],"genre_scores_gemma":[0.9543167,0.0000100002,0.04371732,0.0002869673,0.00002473265,0.00007722917,0.0000632249,0.00004540569,0.001458446],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1246245,"threshold_uncertainty_score":0.9999934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.022086166995421,"score_gpt":0.2517550439481827,"score_spread":0.2296688769527617,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}