{"id":"W7019553412","doi":"","title":"HMG-CoA Reductase Inhibition Reduces T-cell Activation, TNFÎ± Production, and MMP-9 Gene Expression in a Superantigen-mediated Mouse Model of Kawasaki Disease","year":2009,"lang":"en","type":"dissertation","venue":"Library and Archives Canada (Government of Canada)","topic":"Kawasaki Disease and Coronary Complications","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Kawasaki disease; Atorvastatin; Superantigen; Pathogenesis; Elastin; Vasculitis; Vascular smooth muscle; Systemic vasculitis; Inflammation; Cytokine; Gene expression","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001839015,0.0003600015,0.0003333363,0.0004023178,0.0002175998,0.0002638295,0.0001956193,0.0004191152,0.003058743],"category_scores_gemma":[0.00009126726,0.0001821155,0.0002766992,0.0001663576,0.000158112,0.0001280435,0.00009243462,0.0006765576,0.0007989103],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002832659,"about_ca_system_score_gemma":0.000443427,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002618884,"about_ca_topic_score_gemma":0.005548862,"domain_scores_codex":[0.9998938,0.00001439868,0.00001056454,0.00001120911,0.00002984099,0.00004014418],"domain_scores_gemma":[0.9999303,0.000004706152,0.00001603825,0.000005259558,0.00001500331,0.00002868029],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008358876,0.0005065273,0.0002366735,0.00009673531,0.00001619232,0.00007381995,0.00004381143,0.00008882063,0.9923223,0.0001565631,0.000511148,0.005111596],"study_design_scores_gemma":[0.0004498146,0.004618327,0.01248457,0.0000963268,0.0001055015,0.0002144246,0.0001280085,0.0007496656,0.9718198,0.0001576701,0.009160021,0.00001577302],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851833,0.00448692,0.00116669,0.0006310198,0.0001362429,0.00008524455,0.0009291105,0.0001528719,0.007228622],"genre_scores_gemma":[0.9420661,0.01039926,0.003254706,0.0004107149,0.00005929615,0.0001454205,0.002228361,0.00005979473,0.04137623],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003058743,"threshold_uncertainty_score":0.01023245,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005029787370525527,"score_gpt":0.1722991836927608,"score_spread":0.1672693963222352,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}