{"id":"W7021110726","doi":"","title":"Multicentric osteolysis with nodulosis, arthritis, and cardiac defect syndrome: loss of MMP2 leads to increased apoptosis with alteration of apoptotic regulators and caspases and embryonic lethality","year":2014,"lang":"en","type":"other","venue":"Dove Medical Press (Taylor and Francis Group)","topic":"Topological and Geometric Data Analysis","field":"Computer Science","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"MMP2; Apoptosis; Matrix metalloproteinase; Embryonic stem cell; Osteolysis; Caspase; Phenotype; Caspase 8","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007625379,0.0004254763,0.001380805,0.000475044,0.00008727622,0.00009849804,0.0003507659,0.0003251461,0.0000699083],"category_scores_gemma":[0.0004488538,0.0002839132,0.0001011295,0.00084301,0.0007759163,0.0001649054,0.0003716992,0.0002480514,0.000001062083],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001264656,"about_ca_system_score_gemma":0.000005040404,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002899615,"about_ca_topic_score_gemma":0.000282601,"domain_scores_codex":[0.9970047,0.0003515763,0.0004630661,0.0009729398,0.0008472567,0.0003604287],"domain_scores_gemma":[0.9977116,0.0006473704,0.0003556695,0.0006319495,0.00008629262,0.0005670966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0004646351,0.0005836761,0.1191489,0.003026009,0.002128107,0.0001238851,0.0005013651,0.00002845507,0.0001599181,0.003129638,0.0004097982,0.8702956],"study_design_scores_gemma":[0.03858915,0.02187,0.6795793,0.003430922,0.0153074,0.001616338,0.0006070307,0.2103958,0.005961552,0.001040244,0.01027007,0.01133213],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3454443,0.03370147,0.6185453,0.000293379,0.0001442442,0.0009039048,0.0004627662,0.00009430519,0.0004103653],"genre_scores_gemma":[0.997206,0.0003928312,0.002049345,0.00009648547,0.00005815309,0.00003920609,0.00006379489,0.00004412891,0.00005000973],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.8589635,"threshold_uncertainty_score":0.9999613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004989951751962419,"score_gpt":0.2064060438296098,"score_spread":0.2014160920776474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}