{"id":"W7023681484","doi":"","title":"Phase I feasibility study of Magnetic Resonance guided High Intensity Focused Ultrasound-induced hyperthermia, Lyso-Thermosensitive Liposomal Doxorubicin and cyclophosphamide in de novo stage IV breast cancer patients: study protocol of the i-GO study","year":2020,"lang":"en","type":"article","venue":"Utrecht University Repository (Utrecht University)","topic":"Cold Atom Physics and Bose-Einstein Condensates","field":"Physics and Astronomy","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Doxorubicin; Tolerability; Cyclophosphamide; Breast cancer; Clinical endpoint; Phases of clinical research; Hyperthermia; Magnetic resonance imaging","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002016798,0.0004115006,0.0007578523,0.0001696106,0.0003486881,0.0000279264,0.0006385457,0.0000922035,0.00004641755],"category_scores_gemma":[0.00001702218,0.0003941795,0.0001523283,0.001211313,0.0002027617,0.0002844924,0.0005441899,0.0004268292,6.922343e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004068922,"about_ca_system_score_gemma":0.0003323913,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01397101,"about_ca_topic_score_gemma":0.001173418,"domain_scores_codex":[0.9970903,0.0007842808,0.0004672881,0.0008486215,0.000444924,0.000364537],"domain_scores_gemma":[0.997988,0.0001939512,0.000506634,0.0006306305,0.000492712,0.0001880161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002764512,0.01578299,0.954066,0.00004040405,0.0002573892,0.0001630344,0.009154599,0.0000352934,0.01301995,0.000047178,0.00001135653,0.004657324],"study_design_scores_gemma":[0.02696399,0.004250722,0.9105081,0.0001049091,0.0004189337,0.000002547026,0.04237067,0.0001105402,0.01472583,0.00001273176,0.000079661,0.0004513777],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.97205,0.000003342174,0.000002942188,0.00004388785,0.00008365669,0.0268544,0.000133514,0.00003906414,0.0007892398],"genre_scores_gemma":[0.9992179,8.572082e-7,0.00001461075,0.00001460202,0.0000440552,0.00005936007,0.000002756821,0.00002416727,0.0006216704],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04355789,"threshold_uncertainty_score":0.999851,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.015184142790343,"score_gpt":0.2340654382741229,"score_spread":0.2188812954837799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}