{"id":"W7023681484","doi":"","title":"Phase I feasibility study of Magnetic Resonance guided High Intensity Focused Ultrasound-induced hyperthermia, Lyso-Thermosensitive Liposomal Doxorubicin and cyclophosphamide in de novo stage IV breast cancer patients: study protocol of the i-GO study","year":2020,"lang":"en","type":"article","venue":"Utrecht University Repository (Utrecht University)","topic":"Cold Atom Physics and Bose-Einstein Condensates","field":"Physics and Astronomy","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Doxorubicin; Tolerability; Cyclophosphamide; Breast cancer; Clinical endpoint; Phases of clinical research; Hyperthermia; Magnetic resonance imaging","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002657469,0.002706018,0.003272505,0.0005655128,0.0007162229,0.001101081,0.001737728,0.002158363,0.007256149],"category_scores_gemma":[0.001136485,0.0009780928,0.001448908,0.0006108132,0.001595851,0.0007325861,0.0008304735,0.002734205,0.002546181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001269251,"about_ca_system_score_gemma":0.004985616,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001181067,"about_ca_topic_score_gemma":0.001700217,"domain_scores_codex":[0.998818,0.0005609602,0.00005128119,0.0002071998,0.0001030659,0.0002593462],"domain_scores_gemma":[0.9989902,0.00009374446,0.0001498395,0.0001868003,0.00008832543,0.000491079],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7316011,0.1454587,0.004039791,0.001341421,0.0005651851,0.0003446101,0.0004521405,0.002313031,0.08111184,0.0004884811,0.002768773,0.02951493],"study_design_scores_gemma":[0.3643662,0.6155198,0.005212094,0.00005739813,0.0003643654,0.0002237897,0.00009143254,0.0003828782,0.00692228,0.0002055514,0.006618031,0.00003617888],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.890405,0.001606356,0.003925413,0.0005667146,0.000276649,0.09713695,0.002538747,0.0001369806,0.003407083],"genre_scores_gemma":[0.7829662,0.002286557,0.01043304,0.00178797,0.0004545819,0.188812,0.005692015,0.00009402817,0.007473662],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.007256149,"threshold_uncertainty_score":0.02427423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.015184142790343,"score_gpt":0.2340654382741229,"score_spread":0.2188812954837799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}