{"id":"W7024267220","doi":"","title":"Safety, tolerability, and efficacy of PBT2 in Huntington's disease: A phase 2, randomised, double-blind, placebo-controlled trial","year":2015,"lang":"en","type":"article","venue":"Research Bank (Australian Catholic University)","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Population; Cognition; Test (biology); Clinical endpoint; Cognitive test; Stroop effect","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002319827,0.002247016,0.003592727,0.0004757344,0.0005499932,0.001234934,0.001144312,0.002942456,0.0102098],"category_scores_gemma":[0.002255726,0.000817674,0.001448366,0.0004616916,0.00125021,0.001328067,0.0003889509,0.002308318,0.001508872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006561959,"about_ca_system_score_gemma":0.001227781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005356889,"about_ca_topic_score_gemma":0.001108697,"domain_scores_codex":[0.9991907,0.0004006302,0.00005185156,0.0001784094,0.00007476252,0.0001035863],"domain_scores_gemma":[0.9990057,0.0002768106,0.000239376,0.00007241809,0.0001038722,0.0003018074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9847888,0.004294709,0.0002453832,0.0007205355,0.0003378768,0.00004812369,0.00004698578,0.0001366167,0.002532385,0.00006575797,0.0006920538,0.006090934],"study_design_scores_gemma":[0.9609416,0.03746315,0.0006105343,0.00002242289,0.0001188994,0.00002221233,0.000008696027,0.0001497893,0.0001856649,0.00005567276,0.0004136765,0.000007588594],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9717224,0.00594489,0.001274302,0.0009767873,0.0008387881,0.01351475,0.002293688,0.0003312217,0.0031033],"genre_scores_gemma":[0.9485174,0.004913611,0.003532531,0.00202365,0.001093822,0.02940402,0.002252264,0.00006648585,0.0081962],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0102098,"threshold_uncertainty_score":0.03415519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1528434930098986,"score_gpt":0.3824122777755837,"score_spread":0.2295687847656852,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}