{"id":"W7026554397","doi":"","title":"Adult mitochrondrial myopathy associated with generalized respiratory chain deficiency : molecular mechanism and genetic basis","year":2003,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Muscular Dystrophy Association; Howard Hughes Medical Institute","keywords":"Mitochondrial DNA; Mitochondrial myopathy; Oxidative phosphorylation; Mitochondrion; Myopathy; Myocyte; Respiratory chain; Skeletal muscle; Translation (biology)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006570161,0.0005308917,0.0002920977,0.0003709536,0.0002208397,0.0001726096,0.000176488,0.0005125385,0.0013488],"category_scores_gemma":[0.0001230976,0.0001411701,0.0001379896,0.0002083125,0.0003696566,0.0001876351,0.0003318713,0.0002645154,0.0001933025],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001379787,"about_ca_system_score_gemma":0.0001076805,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004163659,"about_ca_topic_score_gemma":0.0004923571,"domain_scores_codex":[0.9999453,0.0000050542,0.000008824504,0.00001947302,0.00001048177,0.00001083223],"domain_scores_gemma":[0.9999312,0.00001015224,0.0000269719,0.000006249736,0.000005691306,0.00001976288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005415063,0.0001119214,0.07924449,0.0004156881,0.00006481961,0.1798479,0.0007305729,0.0003803253,0.7213988,0.001053111,0.0002824452,0.01592841],"study_design_scores_gemma":[0.0001163066,0.001286111,0.4186917,0.00005576985,0.0001730543,0.4701702,0.000542485,0.001614367,0.102648,0.0005952932,0.004076499,0.00003027063],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979362,0.0004791299,0.0008314441,0.00003707267,0.000005951732,0.00001617128,0.00005285084,0.0000423605,0.000598853],"genre_scores_gemma":[0.9981037,0.0005038969,0.0006575157,0.0000281934,0.00001869852,0.0000118813,0.00008118209,0.000006041747,0.0005888752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0013488,"threshold_uncertainty_score":0.004512191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008857898409908133,"score_gpt":0.2175230583910033,"score_spread":0.2086651599810951,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}