{"id":"W7027252715","doi":"","title":"Clinical introduction of mitochondrial replacement therapy in Canada: Towards a robust national strategy","year":2021,"lang":"en","type":"dissertation","venue":"Open MIND","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Disease; MEDLINE; Clinical trial; Key (lock)","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008705773,0.0004871366,0.0006268122,0.001135273,0.006188296,0.006997447,0.002381431,0.008310259,0.01762681],"category_scores_gemma":[0.01129089,0.0003691748,0.0006483176,0.00139602,0.004451694,0.001937411,0.004428071,0.008874542,0.002515687],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.07240849,"about_ca_system_score_gemma":0.4306511,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.8682554,"about_ca_topic_score_gemma":0.9443317,"domain_scores_codex":[0.9921266,0.0009437257,0.0003362326,0.0005146446,0.003432116,0.002646692],"domain_scores_gemma":[0.952554,0.002271269,0.001131437,0.0004498415,0.01427175,0.0293217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0003801678,0.0005804702,0.01092923,0.0004701663,0.00004676462,0.0008231787,0.0008266357,0.00147062,0.003129799,0.02872087,0.7666119,0.1860103],"study_design_scores_gemma":[0.00023747,0.0002880606,0.03087655,0.0008766985,0.00003799998,0.0003055655,0.001516329,0.0009495032,0.00121689,0.005754101,0.9578292,0.0001115841],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.00657965,0.01099361,0.002613072,0.9348146,0.01034169,0.0002820955,0.0005035991,0.0002395141,0.03363222],"genre_scores_gemma":[0.1871269,0.05350151,0.01977555,0.5269034,0.01210116,0.0005384607,0.002059196,0.0005560457,0.1974378],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.9275915,"threshold_uncertainty_score":0.5253628,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05456023221927595,"score_gpt":0.3457667324686288,"score_spread":0.2912065002493528,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}