{"id":"W7028517752","doi":"","title":"Evaluation of Cardiotoxicity Using Blood Biomarkers in Breast Cancer and Lymphoma Patients Undergoing Curative Treatment","year":2019,"lang":"en","type":"dissertation","venue":"MacSphere (McMaster University)","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Cardiotoxicity; Trastuzumab; Ejection fraction; Breast cancer; Biomarker; Chemotherapy; Cancer; Natriuretic peptide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004123554,0.0001711058,0.0003084257,0.0004351047,0.0002086675,0.0003321654,0.0001497033,0.0002709257,0.0006755698],"category_scores_gemma":[0.001655533,0.0001109608,0.0001682201,0.0003805878,0.0001563364,0.0002475796,0.0002016982,0.0002423312,0.0001436319],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002414381,"about_ca_system_score_gemma":0.0002325706,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000945692,"about_ca_topic_score_gemma":0.001444413,"domain_scores_codex":[0.999754,0.00007462745,0.0000302745,0.00004199468,0.00005538315,0.00004363129],"domain_scores_gemma":[0.9991708,0.0001528637,0.0003877975,0.00002506113,0.00009736142,0.0001661823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003419073,0.00004122025,0.9976268,0.000004645622,0.00001089297,0.00008968631,0.000026829,0.00002075265,0.0006063452,0.00000249644,0.00002015301,0.00120828],"study_design_scores_gemma":[0.00001504467,0.0006372226,0.9984398,0.000002943704,0.00001432325,0.0004197183,0.0000727339,0.0001135567,0.0001868204,0.000005930027,0.00009025356,0.000001748068],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995248,0.0001950533,0.00002783866,0.00001549904,0.000001959161,0.000007530276,0.00004801977,0.000001418533,0.0001778911],"genre_scores_gemma":[0.9996631,0.00006884638,0.00005349595,0.00002343585,0.000007143127,0.000008490143,0.0001032842,4.432649e-7,0.00007175227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000945692,"threshold_uncertainty_score":0.00225997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02243044830439779,"score_gpt":0.2620672739017322,"score_spread":0.2396368255973344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}