{"id":"W7029146311","doi":"","title":"Histidine methyltransferase for increased peptide and protein stability","year":2023,"lang":"en","type":"other","venue":"Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU)","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Genome Canada","funders":"","keywords":"Peptide; Histidine; Peptide sequence; Protein stability; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006894617,0.0005931271,0.001110463,0.0004592526,0.0001973075,0.00001074872,0.001013101,0.001894709,0.0009332175],"category_scores_gemma":[0.0003847244,0.0007821417,0.0006664452,0.0005616237,0.001461312,0.00002464495,0.0007037221,0.0005686125,0.00002668771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003265458,"about_ca_system_score_gemma":0.0004095283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00188588,"about_ca_topic_score_gemma":0.01058869,"domain_scores_codex":[0.9969448,0.0002405824,0.0004611175,0.001290633,0.0005164682,0.0005463287],"domain_scores_gemma":[0.997343,0.0002196442,0.0005807352,0.001162848,0.0003290729,0.0003646722],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006480791,0.001039686,0.0007476343,0.001674155,0.001171544,0.000115419,0.00005968852,0.00003454836,0.6951625,0.001112005,0.2877517,0.004650262],"study_design_scores_gemma":[0.01079151,0.002960938,0.006816676,0.001746765,0.0019997,0.0000674706,0.0005209279,0.0001929921,0.03856963,0.000515412,0.9330913,0.002726691],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4814658,0.009169675,0.2012342,0.003954657,0.0009402955,0.02475291,0.01218885,0.003292718,0.2630008],"genre_scores_gemma":[0.6852167,0.005584523,0.04489085,0.00005798216,0.0003715375,0.000008752113,0.001114413,0.001162923,0.2615923],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6565929,"threshold_uncertainty_score":0.9999801,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01158512685258029,"score_gpt":0.212450251909955,"score_spread":0.2008651250573747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}