{"id":"W7030059254","doi":"","title":"Mechanisms underlying the variability in response of Acute Myelogenous Leukemia cells to the immunotoxin AVE9633","year":2009,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"CD33; Immunotoxin; Leukemia; Immunotherapy; Monoclonal antibody; Cytokine; Cell culture; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001692874,0.0001432808,0.000169093,0.0001565475,0.00008978321,0.000259667,0.0001214749,0.0002587225,0.001126898],"category_scores_gemma":[0.0002048668,0.0001162913,0.0002193812,0.0001702648,0.0001184482,0.0001422174,0.0001910338,0.0003640554,0.0003207313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002148171,"about_ca_system_score_gemma":0.00007655864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002377599,"about_ca_topic_score_gemma":0.0002152733,"domain_scores_codex":[0.9998382,0.00002936753,0.00001920669,0.00002771175,0.00005002898,0.00003543985],"domain_scores_gemma":[0.999845,0.00003507778,0.00005979788,0.00002555436,0.00001889177,0.00001556423],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001093133,0.00001551482,0.001468284,0.00001865506,0.000005214469,0.00005084253,0.00002443584,0.0001145378,0.9959681,0.00009992454,0.00004287234,0.002082216],"study_design_scores_gemma":[0.00003041191,0.0007528358,0.2099449,0.00001377818,0.00003647859,0.002130088,0.00014657,0.001741509,0.7816263,0.0003078386,0.003256119,0.00001317734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964862,0.001002484,0.001290306,0.00008660362,0.000006938859,0.00001978515,0.0003106528,0.00003209552,0.0007649896],"genre_scores_gemma":[0.9980762,0.0004641761,0.0003380637,0.00003681555,0.000003418937,0.00001571574,0.0003091348,0.000004256997,0.0007521141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001126898,"threshold_uncertainty_score":0.003769815,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01381610487215567,"score_gpt":0.2428103773473694,"score_spread":0.2289942724752137,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}