{"id":"W7030409930","doi":"","title":"Mitochondrial dynamics and aging: conditions and molecular mechanisms by which genetic alterations of mitochondrial fission and fusion genes promotes longevity","year":2024,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"McGill University","keywords":"Longevity; Mitochondrial fission; mitochondrial fusion; Mitochondrion; Gene; Mitochondrial DNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002153583,0.0001675279,0.0001940921,0.0002266169,0.0002639931,0.0006219115,0.0001680989,0.0003685185,0.004013395],"category_scores_gemma":[0.0002445565,0.0001630708,0.00009435584,0.0001968651,0.0003100496,0.0004922215,0.0003025312,0.0004762316,0.000668272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007282381,"about_ca_system_score_gemma":0.0005953653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002452138,"about_ca_topic_score_gemma":0.004381213,"domain_scores_codex":[0.9999397,0.000005125545,0.000002893666,0.00001625999,0.00002047572,0.00001552107],"domain_scores_gemma":[0.9998891,0.00001471758,0.00002539104,0.000005847084,0.00002115759,0.00004364385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008822876,0.00007528552,0.001129709,0.000174802,0.00001196085,0.0001714407,0.0002736248,0.0004734423,0.9006753,0.008773058,0.01117341,0.07618575],"study_design_scores_gemma":[0.0002056321,0.0005925026,0.1315003,0.0002618438,0.0001195961,0.002018459,0.001231779,0.002856274,0.6419292,0.01682045,0.2023556,0.0001082595],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7651104,0.1361689,0.01207022,0.01933911,0.00140403,0.00008788871,0.001802406,0.000710619,0.06330635],"genre_scores_gemma":[0.8613685,0.074147,0.003468317,0.0006653185,0.00034358,0.00006982448,0.0006865067,0.0001145326,0.05913635],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004013395,"threshold_uncertainty_score":0.01342613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005706376554608499,"score_gpt":0.2285217012470567,"score_spread":0.2228153246924482,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}