{"id":"W7033887125","doi":"","title":"Retinal Architecture in Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS): Insights into Disease Pathogenesis and Biomarkers","year":2021,"lang":"en","type":"article","venue":"UCL Discovery (University College London)","topic":"Machine Learning in Healthcare","field":"Computer Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Retinal; Spinocerebellar ataxia; Nerve fiber layer; Hereditary spastic paraplegia; Retina; Ataxia; Macular degeneration; Spastic","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001599192,0.0002775559,0.0004114522,0.0005063727,0.0002939747,0.00006748676,0.0007739924,0.0001267623,0.00002229902],"category_scores_gemma":[0.0002300459,0.0003086568,0.0001296127,0.001671541,0.0002523196,0.001033351,0.0009908708,0.0003547177,0.000006429562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001850902,"about_ca_system_score_gemma":0.0006571152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000626885,"about_ca_topic_score_gemma":0.002043635,"domain_scores_codex":[0.9973778,0.0006353272,0.0002691774,0.0008829648,0.0004425793,0.0003921193],"domain_scores_gemma":[0.9982474,0.0003253615,0.0002296467,0.0007304496,0.0001494166,0.000317745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003000176,0.001018578,0.7569109,0.003329488,0.0004142381,0.02901157,0.01779365,0.004774715,0.01414049,0.1429566,0.001827501,0.02482213],"study_design_scores_gemma":[0.002581691,0.0002359972,0.9385656,0.0006838872,0.00008339991,0.00008531807,0.001557067,0.04910647,0.0004669931,0.003330825,0.002484811,0.0008180061],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9655318,0.001337863,0.02856286,0.003578821,0.000220566,0.0002957933,0.0001741048,0.00006963553,0.0002286118],"genre_scores_gemma":[0.9926927,0.0001409983,0.005380964,0.0001456022,0.00003812324,0.000002162184,0.0000381994,0.00001720106,0.001544032],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1816546,"threshold_uncertainty_score":0.9999366,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006437914562695299,"score_gpt":0.2078695427429228,"score_spread":0.2014316281802275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}