{"id":"W7033991991","doi":"","title":"Serological and conformational properties of E. coli K92 capsular polysaccharide and its N-propionylated derivative both illustrate that induced antibody does not recognize extended epitopes of polysialic acid: Implications for a comprehensive conjugate vaccine towards Groups B and C N. meningitidis","year":2002,"lang":"en","type":"article","venue":"NPARC","topic":"Bat Biology and Ecology Studies","field":"Agricultural and Biological Sciences","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Epitope; Polysialic acid; Polysaccharide; Antiserum; Conjugate; Antibody; Immune system; Conformational epitope; Antigen","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001223924,0.0004148645,0.0001090513,0.000108309,0.00006186639,0.0001809898,0.0001902152,0.0003361816,0.001101266],"category_scores_gemma":[0.0001880813,0.00009890013,0.0001885294,0.0001136266,0.000167643,0.0001839192,0.000134103,0.0004394821,0.0003393875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001294169,"about_ca_system_score_gemma":0.0001113268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000552293,"about_ca_topic_score_gemma":0.0004037957,"domain_scores_codex":[0.9998963,0.00001720414,0.000009196074,0.00001864911,0.00003287335,0.0000257835],"domain_scores_gemma":[0.9998586,0.00002772567,0.00003441589,0.00002551676,0.00002365986,0.00002989756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000739817,0.00002680183,0.0002931647,0.00001819271,0.000004152141,0.00003148909,0.000008626078,0.00007013397,0.9988309,0.00005103431,0.000008892171,0.0005826789],"study_design_scores_gemma":[0.00001611659,0.0009964118,0.01366105,0.000005293411,0.00002099932,0.0005322691,0.00002702055,0.0009003006,0.9825402,0.00006715066,0.001227569,0.000005608752],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995064,0.0003922607,0.002601332,0.00004586056,0.00001268503,0.00001888037,0.000215818,0.0000182826,0.001630899],"genre_scores_gemma":[0.9971336,0.0001319136,0.001022332,0.00004332162,0.000003963515,0.00001308019,0.0004941251,0.000006977706,0.001150626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001101266,"threshold_uncertainty_score":0.003684044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08606390239970277,"score_gpt":0.2633640188018306,"score_spread":0.1773001164021278,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}