{"id":"W7034343129","doi":"","title":"The synthesis of branched nucleic acid analogs : probing the substrate specificity of the yeast debranching enzyme","year":2000,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Yeast; Nucleic acid; Substrate specificity; Enzyme; Saccharomyces cerevisiae; Substrate (aquarium)","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001944679,0.0002229967,0.0001589493,0.0001126402,0.0001673574,0.0004163742,0.0002289911,0.0003269167,0.001304094],"category_scores_gemma":[0.0003501143,0.0001825129,0.0001419198,0.0001963747,0.0001751081,0.0002637332,0.0001469675,0.0005674663,0.0004519863],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004281009,"about_ca_system_score_gemma":0.0003786529,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001366403,"about_ca_topic_score_gemma":0.002678647,"domain_scores_codex":[0.9999214,0.00001413,0.000004531436,0.00002059249,0.00002544917,0.00001385754],"domain_scores_gemma":[0.9998879,0.00002473277,0.00002116729,0.00001656427,0.00001797387,0.00003147372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001090983,0.0000196681,0.000170187,0.00008922446,0.00000456112,0.00006669349,0.00004729014,0.0004261326,0.9898692,0.0004667577,0.00006775538,0.008663385],"study_design_scores_gemma":[0.000006573897,0.0001078015,0.0003378039,0.000005468862,0.000005414248,0.00008438165,0.00001503381,0.0004228201,0.994279,0.00008072744,0.004650329,0.00000466353],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9632071,0.006448587,0.02100425,0.0003068448,0.00008656788,0.0001069279,0.0004885484,0.0001210924,0.008230057],"genre_scores_gemma":[0.9564515,0.004934486,0.02467548,0.0001073674,0.000012256,0.00003990003,0.001031534,0.00006998448,0.01267739],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001366403,"threshold_uncertainty_score":0.004362643,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006902084519997075,"score_gpt":0.2093561831930122,"score_spread":0.2024540986730152,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}